Table 2.

Demographic details of 264 adult patients from 15 centers who had RIC allografts but did not receive DLIs

CharacteristicNo.
Median age, y (range) 47  (17-66)  
Sex, M/F 165/99  
Sibling donor/unrelated donor/other 186/74/4  
Disease  
 AML and myelodysplastic syndrome 73  
 CML 18 
 CLL 16  
 Myeloma 37 
 NHL 88  
 Hodgkin disease 22 
 Other 10  
Disease status (n = 205)*  
 Favorable 65  (32%) 
 Intermediate 91  (44%)  
 Unfavorable 49  (24%) 
Reasons for not receiving DLI (%)  
 Patient in CR 112  (42)  
 Poor overall condition of patient 70  (27)  
 Patient died before DLI could be given 18  (7)  
 Current GVHD 16  (6)  
 No DLI available 7  (3)  
 Past severe GVHD 4  (2) 
 Other 14  (5)  
 Not known 23  (9) 
CharacteristicNo.
Median age, y (range) 47  (17-66)  
Sex, M/F 165/99  
Sibling donor/unrelated donor/other 186/74/4  
Disease  
 AML and myelodysplastic syndrome 73  
 CML 18 
 CLL 16  
 Myeloma 37 
 NHL 88  
 Hodgkin disease 22 
 Other 10  
Disease status (n = 205)*  
 Favorable 65  (32%) 
 Intermediate 91  (44%)  
 Unfavorable 49  (24%) 
Reasons for not receiving DLI (%)  
 Patient in CR 112  (42)  
 Poor overall condition of patient 70  (27)  
 Patient died before DLI could be given 18  (7)  
 Current GVHD 16  (6)  
 No DLI available 7  (3)  
 Past severe GVHD 4  (2) 
 Other 14  (5)  
 Not known 23  (9) 
*

Disease status is not known for 59 patients.

Reasons included declined by patient (3), had second BMT (2), physician choice (2), had second BMT (2), graft failure (2), had imatinib (1), and planned in future (2).

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