Table 3. Male DNA from PBMCs of healthy... | American Society of Hematology

Table 3.

Male DNA from PBMCs of healthy women and women with SSc with sons older than 10 years at time of blood draw

	Subjects, no.	Observations, no.	Male GenEq cells^3-150		P^3-151	AdjustedP^3-152
	Subjects, no.	Observations, no.	Median	Range	P^3-151	AdjustedP^3-152
All subjects
Controls	26	29	0	0 -3.31	.021	.006
Cases	37	45	0	0 -12.5	.021	.006
With large values excluded^3-153
Controls	26	29	0	0 -3.31	.054	.018
Cases	36	44	0	0 -5.49	.054	.018
With patients with transfusions excluded
Controls	26	29	0	0 -3.31	.135	.035
Cases	31	37	0	0 -6.33	.135	.035

	Subjects, no.	Observations, no.	Male GenEq cells^3-150		P^3-151	AdjustedP^3-152
	Subjects, no.	Observations, no.	Median	Range	P^3-151	AdjustedP^3-152
All subjects
Controls	26	29	0	0 -3.31	.021	.006
Cases	37	45	0	0 -12.5	.021	.006
With large values excluded^3-153
Controls	26	29	0	0 -3.31	.054	.018
Cases	36	44	0	0 -5.49	.054	.018
With patients with transfusions excluded
Controls	26	29	0	0 -3.31	.135	.035
Cases	31	37	0	0 -6.33	.135	.035

GenEq indicates genome equivalent.

F3-150

Per million maternal PBMCs.

F3-151

Results from a regression model with robust variance estimated using the method of generalized estimating equations, weighted by the total number of cells tested.

F3-152

Adjusted for age of last son at time of mother's blood draw.

F3-153

One patient had 3 measurements at the same draw date; instead of averaging the 3 values, we took the lowest value. Another patient had a large value that we excluded to see if these outlying values were influencing the estimates.

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