Table 2. Male DNA in PBMCs from healthy... | American Society of Hematology

Table 2.

Male DNA in PBMCs from healthy women and women with SSc

	Subjects, no.	Observations, no.	Male GenEq cells^*		P^†	AdjustedP^‡
	Subjects, no.	Observations, no.	Median	Range	P^†	AdjustedP^‡
All subjects
Controls	39	47	0	0 -4.37	.14	.032
Cases	39	47	0	0 -12.5	.14	.032
With large values excluded^2-153
Controls	39	47	0	0 -4.37	.31	.047
Cases	38	46	0	0 -5.49	.31	.047
With patients with transfusions excluded
Controls	39	47	0	0 -4.37	.56	.11
Cases	33	39	0	0 -6.33	.56	.11

	Subjects, no.	Observations, no.	Male GenEq cells^*		P^†	AdjustedP^‡
	Subjects, no.	Observations, no.	Median	Range	P^†	AdjustedP^‡
All subjects
Controls	39	47	0	0 -4.37	.14	.032
Cases	39	47	0	0 -12.5	.14	.032
With large values excluded^2-153
Controls	39	47	0	0 -4.37	.31	.047
Cases	38	46	0	0 -5.49	.31	.047
With patients with transfusions excluded
Controls	39	47	0	0 -4.37	.56	.11
Cases	33	39	0	0 -6.33	.56	.11

GenEq indicates genome equivalent.

Per million maternal PBMCs.

†

Results from a regression model with robust variance estimated by means of the method of generalized estimating equations, weighted by the total number of cells tested.

‡

Adjusted for age of last son at time of mother's blood draw.

F2-153

One patient had 3 measurements at the same draw date; instead of averaging the 3 values, we took the lowest value. Another patient had a large value that we excluded to see if these outlying values were influencing the estimates.

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