Table 6. Clinical characteristics of V H... | American Society of Hematology

Table 6.

Clinical characteristics of V_H3-21⁺MCL patients

MCL patient	Sex	Age at diagnosis, y	Stage	Nodal disease	Splenomegaly	BM	Absolute lymphocyte count	Other extranodal sites involved	s-LDH level	IPI	Treatment^6-151	Survival, months
5	M	60	IVA	+	−	+	Normal	Tonsil	7.8	4	2,3,5	78^6-152
14	M	66	IVA	+	+	+	6.9	Gastric	Normal	3	1,2,3,5	34^6-152
23	M	44	IVA	+	−	−	Normal	Orbita, soft tissue	Normal	2	2,4	146^6-152
29	M	59	IVA	+	+	+	13	–	12.6	3	2	31^6-152
32	M	85	IVA	+	++	+	Normal	–	20.0	4	2	5
33	M	49	IVA	+	−	+	Normal	–	11.8	2	2,3,5,4	31^6-152
34	F	48	IVB	+	++	+	Normal	Tonsil, liver	11.6	4	1,2,3,4	37
41	M	80	IVA	+	+	+	Normal	–	13.1	4	2	6^6-152
54	M	79	IVB	+	+	+	Normal	–	9.6	4	2,3,1	52^6-152
58	F	70	IIIA	+	++	−	Normal	–	10.3	3	1,2,5	18^6-152
66	M	62	IVB	+	−	+	18	Colon	Normal	3	2,3,4,5	55^6-152
68	F	65	IVA	+	++	+	4.8	Liver, pleura	14.0	4	2,3,4,5	33^6-152
72	M	70	IIIA	+	−	−	Normal	–	Normal	2	0	8
74	M	49	IVA	+	−	+	Normal	–	NA	NA	2	62^6-152
86	F	79	NA	NA	+	NA	NA	NA	NA	NA	0	0
91	F	66	IVA	+	−	+	Normal	–	Normal	2	1,2,3	32
92	M	51	IVA	+	−	+	Normal	–	Normal	1	2,3,4,5	49^6-152
97	M	68	IVB	+	++	+	50	Colon	Normal	3	2	31^6-152
98	F	58	IVB	+	++	+	Normal	–	12.3	2	2,3,4,5	36
103	M	50	IIIA	+	−	−	Normal	–	Normal	1	2,4	74
105	M	60	IVA	+	−	+	Normal	–	Normal	2	2,3,5	6^6-152

MCL patient	Sex	Age at diagnosis, y	Stage	Nodal disease	Splenomegaly	BM	Absolute lymphocyte count	Other extranodal sites involved	s-LDH level	IPI	Treatment^6-151	Survival, months
5	M	60	IVA	+	−	+	Normal	Tonsil	7.8	4	2,3,5	78^6-152
14	M	66	IVA	+	+	+	6.9	Gastric	Normal	3	1,2,3,5	34^6-152
23	M	44	IVA	+	−	−	Normal	Orbita, soft tissue	Normal	2	2,4	146^6-152
29	M	59	IVA	+	+	+	13	–	12.6	3	2	31^6-152
32	M	85	IVA	+	++	+	Normal	–	20.0	4	2	5
33	M	49	IVA	+	−	+	Normal	–	11.8	2	2,3,5,4	31^6-152
34	F	48	IVB	+	++	+	Normal	Tonsil, liver	11.6	4	1,2,3,4	37
41	M	80	IVA	+	+	+	Normal	–	13.1	4	2	6^6-152
54	M	79	IVB	+	+	+	Normal	–	9.6	4	2,3,1	52^6-152
58	F	70	IIIA	+	++	−	Normal	–	10.3	3	1,2,5	18^6-152
66	M	62	IVB	+	−	+	18	Colon	Normal	3	2,3,4,5	55^6-152
68	F	65	IVA	+	++	+	4.8	Liver, pleura	14.0	4	2,3,4,5	33^6-152
72	M	70	IIIA	+	−	−	Normal	–	Normal	2	0	8
74	M	49	IVA	+	−	+	Normal	–	NA	NA	2	62^6-152
86	F	79	NA	NA	+	NA	NA	NA	NA	NA	0	0
91	F	66	IVA	+	−	+	Normal	–	Normal	2	1,2,3	32
92	M	51	IVA	+	−	+	Normal	–	Normal	1	2,3,4,5	49^6-152
97	M	68	IVB	+	++	+	50	Colon	Normal	3	2	31^6-152
98	F	58	IVB	+	++	+	Normal	–	12.3	2	2,3,4,5	36
103	M	50	IIIA	+	−	−	Normal	–	Normal	1	2,4	74
105	M	60	IVA	+	−	+	Normal	–	Normal	2	2,3,5	6^6-152

Patient 86 died because of splenic rupture at diagnosis; therefore, information was limited.

BM indicates bone marrow involvement.

Normal s-LDH level was 6.7 μkat/L or less.

Leukemic involvement was defined by an absolute lymphocyte count greater than 4 × 10⁹/L.

+ indicates presence; –, absence; and NA, data not available.

0 indicates no treatment; 1, chlorambucil/COP; 2, CHOP/CNOP; 3, rituximab; 4, ASCT; 5, purine/pyrimidine analogues.

Patients who are still alive.