Table 4.

Risk category definitions

Risk subgroupMRC coding9Current study
Favorable inv(16) and t(8;21) inv(16) and t(8;21)  
  CEBPAmutation  
   Without FLT3-ITD and/or adverse cytogenetic features  
Intermediate All others CEBPAmutation  
   With FLT3-ITD  
  All others 
   With/without FLT3-ITD 
Adverse del(5q)/−5, −7, 3q abn,  del(5q)/−5, −7, 3q abn, complex  
  complex  With/without FLT3-ITD and/or CEBPA mutation 
Risk subgroupMRC coding9Current study
Favorable inv(16) and t(8;21) inv(16) and t(8;21)  
  CEBPAmutation  
   Without FLT3-ITD and/or adverse cytogenetic features  
Intermediate All others CEBPAmutation  
   With FLT3-ITD  
  All others 
   With/without FLT3-ITD 
Adverse del(5q)/−5, −7, 3q abn,  del(5q)/−5, −7, 3q abn, complex  
  complex  With/without FLT3-ITD and/or CEBPA mutation 
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