Table 2. Patient characteristics (N =... | American Society of Hematology

Table 2.

Patient characteristics (N = 135 patients)

	Total	CEBPA⁺	CEBPA⁻	P
No. of patients	135	15	120
Median age, y (range)	45 (15-64)	45 (22-63)	45 (15-64)	.59^*
Sex (M/F)	71/64	10/5	61/59	.28^†
WBC, ×10⁹/L (range)	14 (0.6-400)	20 (2.2-170)	13 (0.6-400)	.68^*
FAB subtypes
M0	1	0	1
M1	33	8	25	.02^‡
M2	34	2	32
M4	19	3	16
M5	32	2	30
M6	5	0	5
M7	4	0	4
Unclassified	7	0	7
Cytogenetics (MRC classification)				.06^2-153
Favorable	15	0	15
t(8;21)	9	0	9
Inv(16)	6	0	6
Intermediate	91	15	76
Adverse	14	0	14
Undetermined	15	0	15
FLT3status				.54^†
Wild type	99	10	89
ITD	35	5	30
Induction arm				.79^†
Standard 3 + 7	45	6	39
Double induction	47	4	43
Timed-sequential induction	43	5	38

	Total	CEBPA⁺	CEBPA⁻	P
No. of patients	135	15	120
Median age, y (range)	45 (15-64)	45 (22-63)	45 (15-64)	.59^*
Sex (M/F)	71/64	10/5	61/59	.28^†
WBC, ×10⁹/L (range)	14 (0.6-400)	20 (2.2-170)	13 (0.6-400)	.68^*
FAB subtypes
M0	1	0	1
M1	33	8	25	.02^‡
M2	34	2	32
M4	19	3	16
M5	32	2	30
M6	5	0	5
M7	4	0	4
Unclassified	7	0	7
Cytogenetics (MRC classification)				.06^2-153
Favorable	15	0	15
t(8;21)	9	0	9
Inv(16)	6	0	6
Intermediate	91	15	76
Adverse	14	0	14
Undetermined	15	0	15
FLT3status				.54^†
Wild type	99	10	89
ITD	35	5	30
Induction arm				.79^†
Standard 3 + 7	45	6	39
Double induction	47	4	43
Timed-sequential induction	43	5	38

By the Mann-Whitney test.

By the Fisher exact test.

By the Fisher exact test comparing M1 subtype versus all other FAB subtypes.

By the Fisher exact test performed on the 4-subgroup repartition, including favorable, intermediate, adverse, and undetermined cytogenetics.