Table 1. Circulating PMN and mononuclear... | American Society of Hematology

Table 1.

Circulating PMN and mononuclear cell counts after different treatments

Treatment at 0 h		Treatment at 4 h		PMN leukocytes/μL blood	Mononuclear cells/μL blood
Inhibitors	Stimulus	Inhibitors	Stimulus	PMN leukocytes/μL blood	Mononuclear cells/μL blood
None	Saline	None	None	780 ± 80	2820 ± 320
None	Saline	None	RB6-8C5	40 ± 40^*	3100 ± 530
None	TNF-α	None	None	670 ± 120	1750 ± 340
None	TNF-α	None	RB6-8C5	20 ± 20^*	420 ± 60^*
E-selectin mAb	TNF-α	Heparin + P-selectin mAb	None	1480 ± 250^†	1200 ± 140
E-selectin mAb	TNF-α	Heparin + P-selectin mAb	RB6-8C5	140 ± 110^‡	540 ± 110^*

Treatment at 0 h		Treatment at 4 h		PMN leukocytes/μL blood	Mononuclear cells/μL blood
Inhibitors	Stimulus	Inhibitors	Stimulus	PMN leukocytes/μL blood	Mononuclear cells/μL blood
None	Saline	None	None	780 ± 80	2820 ± 320
None	Saline	None	RB6-8C5	40 ± 40^*	3100 ± 530
None	TNF-α	None	None	670 ± 120	1750 ± 340
None	TNF-α	None	RB6-8C5	20 ± 20^*	420 ± 60^*
E-selectin mAb	TNF-α	Heparin + P-selectin mAb	None	1480 ± 250^†	1200 ± 140
E-selectin mAb	TNF-α	Heparin + P-selectin mAb	RB6-8C5	140 ± 110^‡	540 ± 110^*

P < .01 for significant difference from value prior to RB6-8C5 treatment.

P < .05 for significant difference from TNF-α-stimulated mouse without selectin blockade/heparin.

P < .05 for significant difference from value prior to RB6-8C5 treatment.