Univariable and multivariable analysis of highEVI1 expression as prognostic factor for survival
| . | EFS . | OS . | ||
|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Univariable analysis | ||||
| HighEVI1expression | 1.82 (1.25-2.67) | .002 | 1.85 (1.25-2.73) | .002 |
| Multivariable analysis | ||||
| Cytogenetics risk | <.0001 | <.0001 | ||
| Favorable | 1 (—) | 1 (—) | ||
| Intermediate | 2.29 (1.47-3.57) | 2.85 (1.71-4.77) | ||
| Unfavorable | 3.10 (1.78-5.41) | 4.20 (2.26-7.83) | ||
| Age, y | .64 | .56 | ||
| Younger than 35 | 1 (—) | 1 (—) | ||
| 35-50 | 0.98 (0.69-1.38) | 1.12 (0.78-1.61) | ||
| Older than 50 | 1.12 (0.81-1.57) | 1.21 (0.85-1.73) | ||
| FLT3 mutation vs no mutation | 1.48 (1.11-1.98) | .01 | 1.53 (1.12-2.09) | .009 |
| High EVI1expression | 1.47 (0.96-2.25) | .09 | 1.48 (0.96-2.29) | .09 |
| . | EFS . | OS . | ||
|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Univariable analysis | ||||
| HighEVI1expression | 1.82 (1.25-2.67) | .002 | 1.85 (1.25-2.73) | .002 |
| Multivariable analysis | ||||
| Cytogenetics risk | <.0001 | <.0001 | ||
| Favorable | 1 (—) | 1 (—) | ||
| Intermediate | 2.29 (1.47-3.57) | 2.85 (1.71-4.77) | ||
| Unfavorable | 3.10 (1.78-5.41) | 4.20 (2.26-7.83) | ||
| Age, y | .64 | .56 | ||
| Younger than 35 | 1 (—) | 1 (—) | ||
| 35-50 | 0.98 (0.69-1.38) | 1.12 (0.78-1.61) | ||
| Older than 50 | 1.12 (0.81-1.57) | 1.21 (0.85-1.73) | ||
| FLT3 mutation vs no mutation | 1.48 (1.11-1.98) | .01 | 1.53 (1.12-2.09) | .009 |
| High EVI1expression | 1.47 (0.96-2.25) | .09 | 1.48 (0.96-2.29) | .09 |
— indicates not applicable.