PCR and sequence analysis of the rearranged IgH gene of KSHV-positive foci in case 1
| KSHV-positive foci . | No. of clones . | Clones with identical VH and CDR3 . | Mutation in VH . |
|---|---|---|---|
| Focus 1 | 12 | 4 (DP77) | 5R, 3s |
| 7 (DP88) | 2R, 2s | ||
| 1 (Yac7) | 4R | ||
| Focus 2 | 4 | 3 (DP58) | 2R |
| 1 (DP63) | 4R, 2s |
| KSHV-positive foci . | No. of clones . | Clones with identical VH and CDR3 . | Mutation in VH . |
|---|---|---|---|
| Focus 1 | 12 | 4 (DP77) | 5R, 3s |
| 7 (DP88) | 2R, 2s | ||
| 1 (Yac7) | 4R | ||
| Focus 2 | 4 | 3 (DP58) | 2R |
| 1 (DP63) | 4R, 2s |
R indicates replacement mutation; s, silent mutation.