HSCT for adult de novo EL in first CR
| Cytogenetic risk groups (SWOG criteria) . | Identical-sibling allogeneic HSCT n = 43 . | Autologous HSCT n = 36 . |
|---|---|---|
| Favorable | n = 0 | n = 0 |
| n = 0 | ||
| Intermediate | n = 30 | n = 28 |
| n = 58 | Normal, n = 28 | Normal, n = 24 |
| Trisomy 8, n = 2 | Trisomy 8, n = 4 | |
| Unfavorable | n = 8 | n = 4 |
| n = 12 | abn 3q and 9q | abn 20q and t(5;7),del(17q) |
| abn 11q | −7 in complex karyotype | |
| del(7) | abn 3q, −7, and ins(6p) | |
| abn 11q | del(5q),−7, abn 17p in complex karyotype | |
| abn 3q | ||
| −7 in complex karyotype | ||
| abn 3q | ||
| abn 20q | ||
| Unknown | n = 5 | n = 4 |
| n = 9 | i(18q) | Tetraploidy |
| Pseudo/hypodiploidy | Hypodiploidy | |
| del(6) | Hypodiploidy | |
| −20,+mar | Pseudo near-triploidy and tetraploidy | |
| Hypodiploidy |
| Cytogenetic risk groups (SWOG criteria) . | Identical-sibling allogeneic HSCT n = 43 . | Autologous HSCT n = 36 . |
|---|---|---|
| Favorable | n = 0 | n = 0 |
| n = 0 | ||
| Intermediate | n = 30 | n = 28 |
| n = 58 | Normal, n = 28 | Normal, n = 24 |
| Trisomy 8, n = 2 | Trisomy 8, n = 4 | |
| Unfavorable | n = 8 | n = 4 |
| n = 12 | abn 3q and 9q | abn 20q and t(5;7),del(17q) |
| abn 11q | −7 in complex karyotype | |
| del(7) | abn 3q, −7, and ins(6p) | |
| abn 11q | del(5q),−7, abn 17p in complex karyotype | |
| abn 3q | ||
| −7 in complex karyotype | ||
| abn 3q | ||
| abn 20q | ||
| Unknown | n = 5 | n = 4 |
| n = 9 | i(18q) | Tetraploidy |
| Pseudo/hypodiploidy | Hypodiploidy | |
| del(6) | Hypodiploidy | |
| −20,+mar | Pseudo near-triploidy and tetraploidy | |
| Hypodiploidy |
Results of karyotype at diagnosis classified according to the SWOG cytogenetics risk groups in 79 informative patients—52 with normal karyotype and 27 with abnormal karyotype.