Clinical description of patients at diagnosis
Patient . | Lille score at diagnosis . | Time since diagnosis (y) . | Transfusion requirements . | Therapy prior to blood sampling . | Leukocyte count (103/mL) . | Percentage of immature cells in the blood . | Hemoglobin level (g/dL) . | Platelet count (106/mL) . | Analysis in DDRT-PCR . | Analysis in semiquantitative PCR . | Analysis in quantitative PCR . | Analysis in Western-blot . | Analysis in flow cytometry . |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P1 | Int | 5 | No | No | 35 000 | 25 | 11.0 | 550 | + | + | + | + | |
P2 | High | 8.5 | Yes | HU + PU | 74 100 | 39 | 9.9 | 82 | + | + | + | + | |
P3 | Int | 4 | Yes | HU | 21 000 | 15 | 7.7 | 92 | + | + | + | ||
P4 | Low | 0 | No | No | 12 700 | 9 | 11.8 | 253 | + | + | + | + | |
P5 | Low | 0 | No | HU | 9 300 | 5 | 11.4 | 174 | + | + | + | ||
P6 | High | 2 | No | HU + PU | 17 400 | 43 | 11.4 | 203 | + | + | + | + | |
P7 | Low | 2 | No | HU | 9 500 | 6 | 12.7 | 256 | + | ||||
P8 | Int | 1 | Yes | HU | 4 600 | 15 | 11.4 | 69 | + | ||||
P9 | Int | 1 | Yes | HU | 13 500 | 12 | 10.2 | 107 | + | ||||
P10 | Low | 6 | No | HU | 18 000 | 5 | 12.8 | 420 | + |
Patient . | Lille score at diagnosis . | Time since diagnosis (y) . | Transfusion requirements . | Therapy prior to blood sampling . | Leukocyte count (103/mL) . | Percentage of immature cells in the blood . | Hemoglobin level (g/dL) . | Platelet count (106/mL) . | Analysis in DDRT-PCR . | Analysis in semiquantitative PCR . | Analysis in quantitative PCR . | Analysis in Western-blot . | Analysis in flow cytometry . |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P1 | Int | 5 | No | No | 35 000 | 25 | 11.0 | 550 | + | + | + | + | |
P2 | High | 8.5 | Yes | HU + PU | 74 100 | 39 | 9.9 | 82 | + | + | + | + | |
P3 | Int | 4 | Yes | HU | 21 000 | 15 | 7.7 | 92 | + | + | + | ||
P4 | Low | 0 | No | No | 12 700 | 9 | 11.8 | 253 | + | + | + | + | |
P5 | Low | 0 | No | HU | 9 300 | 5 | 11.4 | 174 | + | + | + | ||
P6 | High | 2 | No | HU + PU | 17 400 | 43 | 11.4 | 203 | + | + | + | + | |
P7 | Low | 2 | No | HU | 9 500 | 6 | 12.7 | 256 | + | ||||
P8 | Int | 1 | Yes | HU | 4 600 | 15 | 11.4 | 69 | + | ||||
P9 | Int | 1 | Yes | HU | 13 500 | 12 | 10.2 | 107 | + | ||||
P10 | Low | 6 | No | HU | 18 000 | 5 | 12.8 | 420 | + |
Presented are the clinical description of patients at diagnosis (Lille score19), time since diagnosis, transfusion requirement at the time of blood collection, therapy prior to blood collection, leukocyte count at the time of blood collection, and experiments performed with each sample.
HU indicates hydroxyurea; PU, 6-mercaptopurine.