Toxicity associated with VRD, as recorded according to Common Terminology Criteria for Adverse Events version 4.03
| . | All grades . | Grade 3-4 . |
|---|---|---|
| Neutropenia | 3 (6) | 1 (3) |
| Thrombocytopenia | 4 (12) | 2 (6) |
| Anemia | 15 (44) | 2 (6) |
| Rash | 14 (42) | 5 (15) |
| Fatigue | 12 (35) | 3 (9) |
| Increased creatinine | 17 (50) | 2 (6) |
| Peripheral sensory neuropathy | 13 (38) | 0 |
| Diarrhea | 5 (15) | 3 (9) |
| Fever NOS | 7 (21) | 4 (12) |
| Infection | 8 (24) | 3 (9) |
| Constipation | 5 (15) | 3 (9) |
| Thrombosis | 1 (3) | 1 (3) |
| Peripheral edema | 5 (15) | 1 (3) |
| LFT elevation | 3 (9) | 1 (3) |
| Muscle cramps | 1 (3) | 0 |
| Facial nerve palsy | 1 (3) | 0 |
| . | All grades . | Grade 3-4 . |
|---|---|---|
| Neutropenia | 3 (6) | 1 (3) |
| Thrombocytopenia | 4 (12) | 2 (6) |
| Anemia | 15 (44) | 2 (6) |
| Rash | 14 (42) | 5 (15) |
| Fatigue | 12 (35) | 3 (9) |
| Increased creatinine | 17 (50) | 2 (6) |
| Peripheral sensory neuropathy | 13 (38) | 0 |
| Diarrhea | 5 (15) | 3 (9) |
| Fever NOS | 7 (21) | 4 (12) |
| Infection | 8 (24) | 3 (9) |
| Constipation | 5 (15) | 3 (9) |
| Thrombosis | 1 (3) | 1 (3) |
| Peripheral edema | 5 (15) | 1 (3) |
| LFT elevation | 3 (9) | 1 (3) |
| Muscle cramps | 1 (3) | 0 |
| Facial nerve palsy | 1 (3) | 0 |
Values represent n (%) of patients.
LFT, liver function test; NOS, not otherwise specified.