Nonhematological toxicity (grades 3-4) associated with remission-induction therapy
| . | Group 1 n = 102 . | Group 2 n = 160 . | Group 1 vs group 2 . | Group 2A (n = 106) . | Group 2B (n = 53) . | Group 2A vs group 2B . |
|---|---|---|---|---|---|---|
| . | . | |||||
| n (%) . | n (%) . | P . | n (%) . | n (%) . | P . | |
| Liver | 4 (3.9) | 12 (7.5) | .23 | 8 (7.5) | 4 (7.5) | >.99 |
| Renal | 0 (.0) | 7 (4.4) | .034-150 | 6 (5.7) | 1 (1.9) | .28 |
| CNS | 0 (.0) | 6 (3.8) | .11 | 4 (3.8) | 2 (3.8) | >.99 |
| GIT | 5 (4.9) | 40 (25) | <.014-150 | 17 (16) | 23 (43) | <.014-150 |
| Lung | 3 (3.0) | 15 (9.4) | .044-150 | 11 (10.4) | 4 (7.5) | .57 |
| Heart | 0 (0) | 4 (2.5) | .11 | 4 (3.8) | 0 (0) | .034-150 |
| Infection | 29 (28) | 26 (16.3) | .024-150 | 22 (21) | 4 (7.5) | .034-150 |
| . | Group 1 n = 102 . | Group 2 n = 160 . | Group 1 vs group 2 . | Group 2A (n = 106) . | Group 2B (n = 53) . | Group 2A vs group 2B . |
|---|---|---|---|---|---|---|
| . | . | |||||
| n (%) . | n (%) . | P . | n (%) . | n (%) . | P . | |
| Liver | 4 (3.9) | 12 (7.5) | .23 | 8 (7.5) | 4 (7.5) | >.99 |
| Renal | 0 (.0) | 7 (4.4) | .034-150 | 6 (5.7) | 1 (1.9) | .28 |
| CNS | 0 (.0) | 6 (3.8) | .11 | 4 (3.8) | 2 (3.8) | >.99 |
| GIT | 5 (4.9) | 40 (25) | <.014-150 | 17 (16) | 23 (43) | <.014-150 |
| Lung | 3 (3.0) | 15 (9.4) | .044-150 | 11 (10.4) | 4 (7.5) | .57 |
| Heart | 0 (0) | 4 (2.5) | .11 | 4 (3.8) | 0 (0) | .034-150 |
| Infection | 29 (28) | 26 (16.3) | .024-150 | 22 (21) | 4 (7.5) | .034-150 |
GIT indicates gastrointestinal system.
P < .05.