AID expression in DLBCL
| . | n . | AIDpositive . | Preceded by FL . | SHM greater than 6% . |
|---|---|---|---|---|
| CD10+ | 5 | 5 of 5 | 3 of 5 | 3 of 3 |
| CD10− | 8 | 8 of 8 | 0 of 8 | 5 of 5 |
| . | n . | AIDpositive . | Preceded by FL . | SHM greater than 6% . |
|---|---|---|---|---|
| CD10+ | 5 | 5 of 5 | 3 of 5 | 3 of 3 |
| CD10− | 8 | 8 of 8 | 0 of 8 | 5 of 5 |
CD10 protein, AID mRNA, and somatic hypermutation of theIgH gene in DLBCL. In 13 patients with DLBCL, CD10 protein expression was analyzed by immunohistochemistry. AID mRNA expression was analyzed by RT-PCR. Three of the CD10+ patients showed progression from documented FL. The variable region exons of the IgH gene were sequenced in 3 of the CD10+ and in 5 of the CD10− patients.