Steady state leukocyte count in sickle cell stroke cases is associated with VCAM1 promoter genotype
. | Stroke . | Control . | ||
---|---|---|---|---|
T − 1599G | TT (n = 43) | TG (n = 8) | TT (n = 47) | TG (n = 3) |
Mean WBC (SD)6-150 | 15.7 (3.7)6-151,6-152 | 13.1 (1.1)6-151 | 13.7 (3.3)6-152 | 12.0 (3.0) |
. | Stroke . | Control . | ||
---|---|---|---|---|
T − 1599G | TT (n = 43) | TG (n = 8) | TT (n = 47) | TG (n = 3) |
Mean WBC (SD)6-150 | 15.7 (3.7)6-151,6-152 | 13.1 (1.1)6-151 | 13.7 (3.3)6-152 | 12.0 (3.0) |
SD indicates standard deviation.
Values for white blood cell (WBC) counts are 106/μL.
Mean values are significantly different for TT strokes versus TG stokes by Mann-Whitney test (U statistic = 78,P = .02).
Mean values are significantly different for strokes versus controls of the TT genotype by Mann-Whitney test (U statistic = 674, P = .004).