Table 2. Flow cytometric analysis of... | American Society of Hematology

Table 2.

Flow cytometric analysis of T-cell responses to WT1 (126), WT1 (187), and proteinase 3 in AML patients

Patient	No peptide	WT1 (126)	WT1 (187)	PR3 (169)
1	0.04	0.27^*,^†	0.27^*,^†	0.08
2	0.04	0.10^*	0.05	0.06
3	0.06	0.08	0.21^*	0.09
4	0.18	0.16	0.23	0.60^*
5	0.18	0.11^†	0.11^†	0.18
6	NA	—	—	—
7	0.36	0.40^†	0.40^†	0.38
8	0.02	0.04	0.04	0.05
9	0.02	0.03	0.03	0.02
10^‡	0.64	ND	ND	1.34^*
	0.13	ND	ND	0.28^*
	0.03	ND	ND	0.45^*
	0.31	0.21	0.32	0.69^*
11	0.28	0.26^†	0.26^†	0.41
12	0.07	0.12^†	0.12^†	0.21^*
13	0.04	0.07	0.07	0.14^*
14	NA	—	—	—
15	NA	—	—	—

Patient	No peptide	WT1 (126)	WT1 (187)	PR3 (169)
1	0.04	0.27^*,^†	0.27^*,^†	0.08
2	0.04	0.10^*	0.05	0.06
3	0.06	0.08	0.21^*	0.09
4	0.18	0.16	0.23	0.60^*
5	0.18	0.11^†	0.11^†	0.18
6	NA	—	—	—
7	0.36	0.40^†	0.40^†	0.38
8	0.02	0.04	0.04	0.05
9	0.02	0.03	0.03	0.02
10^‡	0.64	ND	ND	1.34^*
	0.13	ND	ND	0.28^*
	0.03	ND	ND	0.45^*
	0.31	0.21	0.32	0.69^*
11	0.28	0.26^†	0.26^†	0.41
12	0.07	0.12^†	0.12^†	0.21^*
13	0.04	0.07	0.07	0.14^*
14	NA	—	—	—
15	NA	—	—	—

Percentage of CD3/CD8/IFN-γ–secreting T cells in response to no peptide, WT1 peptides, or proteinase 3 peptide, respectively.

Frequencies correspond to positive T-cell responses (2-fold or higher compared with PBMCs not exposed to peptide, with a minimum of 0.05% IFN-γ–producing CD3 CD8 T cells).

†

T-cell response was analyzed against both WT1 peptides in one sample.

‡

Analysis of different time points in patient 10.

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