Severity of anemia in splenectomized patients before splenectomy and in unsplenectomized members of the same family (HS pairs)
| Splenectomized family member . | Unsplenectomized family member . | Deficiency . | ||||||
|---|---|---|---|---|---|---|---|---|
| Patient ID . | Sex . | Before splenectomy . | ||||||
| Hb, g/dL . | Reticulocytes, % . | Patient ID . | Sex . | Hb, g/dL . | Reticulocytes, % . | |||
| AZ2 | F | 12.5 | 3.0 | AZ1 | M | 15.9 | 2.4 | B3 |
| AZ4 | M | 13.6 | 6.0 | AZ3 | F | 12.5 | 2.1 | B3 |
| AZ5 | M | 16.6 | 2.9 | B3 | ||||
| AZ7 | M | 13.7 | 11.4 | AZ6.1 | M | 13.6 | 5.0 | B3 |
| AZ9 | M | 12.0 | 10.0 | AZ8 | F | 12.1 | 5.0 | B3 |
| AZ10 | F | 11.6 | 10.4 | B3 | ||||
| AZ16 | M | 11.5 | 8.3 | AZ15 | M | 13.1 | 8.3 | Sp/ank |
| AZ18 | M | 13.1 | 13.2 | AZ17 | M | 12.2 | 8.8 | Sp/ank |
| EG6 | F | 8.9 | 11.0 | EG5 | M | 10.7 | 8.8 | Sp/ank |
| HL2 | F | NA | NA | HL1 | F | 13.1 | 9.5 | Sp/ank |
| LR2 | M | 13.2 | 5.9 | LR1 | M | 9.6 | 15.3 | B3 |
| SE2 | F | 10.3 | 18.0 | SE1 | M | 10.1 | 12.6 | Sp/ank |
| WR2 | F | NA | NA | WR1.1 | F | 11.9 | 10.6 | B3 |
| WR1.2 | F | 11.9 | 10.6 | WR3 | M | 15.1 | — | B3 |
| WR5 | M | 11.7 | 13.5 | WR4 | M | 10.4 | 6.9 | B3 |
| Splenectomized family member . | Unsplenectomized family member . | Deficiency . | ||||||
|---|---|---|---|---|---|---|---|---|
| Patient ID . | Sex . | Before splenectomy . | ||||||
| Hb, g/dL . | Reticulocytes, % . | Patient ID . | Sex . | Hb, g/dL . | Reticulocytes, % . | |||
| AZ2 | F | 12.5 | 3.0 | AZ1 | M | 15.9 | 2.4 | B3 |
| AZ4 | M | 13.6 | 6.0 | AZ3 | F | 12.5 | 2.1 | B3 |
| AZ5 | M | 16.6 | 2.9 | B3 | ||||
| AZ7 | M | 13.7 | 11.4 | AZ6.1 | M | 13.6 | 5.0 | B3 |
| AZ9 | M | 12.0 | 10.0 | AZ8 | F | 12.1 | 5.0 | B3 |
| AZ10 | F | 11.6 | 10.4 | B3 | ||||
| AZ16 | M | 11.5 | 8.3 | AZ15 | M | 13.1 | 8.3 | Sp/ank |
| AZ18 | M | 13.1 | 13.2 | AZ17 | M | 12.2 | 8.8 | Sp/ank |
| EG6 | F | 8.9 | 11.0 | EG5 | M | 10.7 | 8.8 | Sp/ank |
| HL2 | F | NA | NA | HL1 | F | 13.1 | 9.5 | Sp/ank |
| LR2 | M | 13.2 | 5.9 | LR1 | M | 9.6 | 15.3 | B3 |
| SE2 | F | 10.3 | 18.0 | SE1 | M | 10.1 | 12.6 | Sp/ank |
| WR2 | F | NA | NA | WR1.1 | F | 11.9 | 10.6 | B3 |
| WR1.2 | F | 11.9 | 10.6 | WR3 | M | 15.1 | — | B3 |
| WR5 | M | 11.7 | 13.5 | WR4 | M | 10.4 | 6.9 | B3 |
A23 to A25 belong to the same family as A28 to A210. WR1.1 to WR5 are from the same pedigree.74
NA indicates not available because splenectomy was performed more than 15 years earlier; —, not done, but bilirubin concentration 3 times normal.