Table 2. Risk factors for OS and EFS:... | American Society of Hematology

Table 2.

Risk factors for OS and EFS: multivariate analysis

Risk factors	Overall survival RR (95% CI)	Event-free survival RR (95% CI)
Age at diagnosis, y
1 to 10	1.0	1.0
Younger than 1	3.8 (3.1-4.6)^*	3.3 (2.8-4.0)^*
Older than 10	2.3 (2.1-2.6)^*	1.8 (1.6-1.9)^*
Initial WBC count
Lower than 50 000/mL	1.0	1.0
50 000/mL or higher	1.7 (1.5-1.9)^*	1.4 (1.2-1.5)^*
Initial platelet count
50 000/mL or higher	1.0	1.0
Less than 50 000/mL	1.0 (0.9-1.1)^2-153	1.1 (1.0-1.2)^‡
Sex
Female	1.0	1.0
Male	1.1 (1.0-1.3)^†	1.2 (1.1-1.3)^*
Liver size
Normal	1.0	1.0
Enlarged	1.1 (0.9-1.2)^2-153	1.2 (1.0-1.3)^†
Spleen size
Normal	1.0	1.0
Enlarged	1.3 (1.2-1.4)^*	1.1 (1.0-1.3)^‡
Era
Recent	1.0	1.0
Early	1.4 (1.3-1.6)^*	1.5 (1.4-1.6)^*
Ethnicity
White	1.0	1.0
Black	1.4 (1.1-1.6)^*	1.4 (1.2-1.7)^*
Hispanic	1.4 (1.2-1.6)^*	1.3 (1.2-1.5)^*
Asian	0.6 (0.4-0.9)^‡	0.8 (0.6-1.1)^2-153

Risk factors	Overall survival RR (95% CI)	Event-free survival RR (95% CI)
Age at diagnosis, y
1 to 10	1.0	1.0
Younger than 1	3.8 (3.1-4.6)^*	3.3 (2.8-4.0)^*
Older than 10	2.3 (2.1-2.6)^*	1.8 (1.6-1.9)^*
Initial WBC count
Lower than 50 000/mL	1.0	1.0
50 000/mL or higher	1.7 (1.5-1.9)^*	1.4 (1.2-1.5)^*
Initial platelet count
50 000/mL or higher	1.0	1.0
Less than 50 000/mL	1.0 (0.9-1.1)^2-153	1.1 (1.0-1.2)^‡
Sex
Female	1.0	1.0
Male	1.1 (1.0-1.3)^†	1.2 (1.1-1.3)^*
Liver size
Normal	1.0	1.0
Enlarged	1.1 (0.9-1.2)^2-153	1.2 (1.0-1.3)^†
Spleen size
Normal	1.0	1.0
Enlarged	1.3 (1.2-1.4)^*	1.1 (1.0-1.3)^‡
Era
Recent	1.0	1.0
Early	1.4 (1.3-1.6)^*	1.5 (1.4-1.6)^*
Ethnicity
White	1.0	1.0
Black	1.4 (1.1-1.6)^*	1.4 (1.2-1.7)^*
Hispanic	1.4 (1.2-1.6)^*	1.3 (1.2-1.5)^*
Asian	0.6 (0.4-0.9)^‡	0.8 (0.6-1.1)^2-153

P .001.

.001 < P .01.

.01 < P < .05.

P = NS.