Table 1.

The expected (Hardy-Weinberg) and observed distribution of Cys282Tyr alleles among the 19733 subjects who reported only northern or western European ancestry

GenotypeExpectedObserved
wt/wt 17 116 17 130 
wt/Cys282Tyr 2 524 2 496 
Cys282Tyr/Cys282Tyr 93 107 
Total 19 733 19 733 
GenotypeExpectedObserved
wt/wt 17 116 17 130 
wt/Cys282Tyr 2 524 2 496 
Cys282Tyr/Cys282Tyr 93 107 
Total 19 733 19 733 

The Cys282Tyr gene frequency was 0.06867; wt gene frequency, 0.93133. wt indicates wild type.