Leukocytes recovered from peripheral organs of GVHD mice*
. | Spleen . | Liver . | Lung . |
---|---|---|---|
B6 female → BALB.B male | |||
Day 3 after transplantation | 2 × 106 | 3 × 105 | 1 × 105 |
% donor CD4 T cells† | 11 | 4 | 15 |
% donor CD8 T cells† | 35 | 52 | 56 |
Day 7 after transplantation | 2.6 × 107 | 2.7 × 106 | 2.7 × 106 |
% donor CD4 T cells† | 90 | 99 | 99 |
% donor CD8 T cells† | 87 | 97 | 97 |
Day 14‡ | 6.4 × 107 | 6 × 106 | 4.3 × 106 |
Day 28‡ | 2.3 × 107 | 8.8 × 106 | 10.3 × 106 |
BALB.B male → BALB.B male | |||
Day 14 after transplantation | 4.8 × 107 | 1.2 × 106 | 1.2 × 106 |
. | Spleen . | Liver . | Lung . |
---|---|---|---|
B6 female → BALB.B male | |||
Day 3 after transplantation | 2 × 106 | 3 × 105 | 1 × 105 |
% donor CD4 T cells† | 11 | 4 | 15 |
% donor CD8 T cells† | 35 | 52 | 56 |
Day 7 after transplantation | 2.6 × 107 | 2.7 × 106 | 2.7 × 106 |
% donor CD4 T cells† | 90 | 99 | 99 |
% donor CD8 T cells† | 87 | 97 | 97 |
Day 14‡ | 6.4 × 107 | 6 × 106 | 4.3 × 106 |
Day 28‡ | 2.3 × 107 | 8.8 × 106 | 10.3 × 106 |
BALB.B male → BALB.B male | |||
Day 14 after transplantation | 4.8 × 107 | 1.2 × 106 | 1.2 × 106 |
Means of nucleated cells from 3 mice.
Percent of donor-derived T cells in total CD4 or CD8 T cells. Donor B6 cells were distinguished from recipient BALB.B cells by allelic expression of β2-m: B6, β2-mb; BALB.B, β2-ma.
About 100% of lymphocytes were donor-derived. Data are representative of 2 experiments.