Gene expression profiles from FAC-treated HeLa cells
| Gene name . | Expression change . | |
|---|---|---|
| Hemin . | FAC . | |
| HO-1 | +8.0 ± 0.2 | +2.0 ± 0.2 |
| Hsp70D | +3.0 ± 0.5 | +1.6 ± 0.1 |
| mHsp70 | +1.8 ± 0.1 | +1.4 ± 0.05 |
| L-Fer | +1.8 ± 0.1 | +1.5 ± 0.01 |
| Gas-3 | +1.7 ± 0.1 | +1.5 ± 0.01 |
| Hsp105α | +2.0 ± 0.2 | — |
| Gas-1 | +1.7 ± 0.1 | — |
| TfR-1 | −3.0 ± 1.2 | −2.0 ± 0.5 |
| Mt-2 | −2.3 ± 0.3 | −1.5 ± 0.2 |
| c-jun | −2.0 ± 0.3 | — |
| lysyl oxidase | −2.4 ± 0.4 | — |
| Hif-1α | −2.0 ± 0.2 | — |
| Gene name . | Expression change . | |
|---|---|---|
| Hemin . | FAC . | |
| HO-1 | +8.0 ± 0.2 | +2.0 ± 0.2 |
| Hsp70D | +3.0 ± 0.5 | +1.6 ± 0.1 |
| mHsp70 | +1.8 ± 0.1 | +1.4 ± 0.05 |
| L-Fer | +1.8 ± 0.1 | +1.5 ± 0.01 |
| Gas-3 | +1.7 ± 0.1 | +1.5 ± 0.01 |
| Hsp105α | +2.0 ± 0.2 | — |
| Gas-1 | +1.7 ± 0.1 | — |
| TfR-1 | −3.0 ± 1.2 | −2.0 ± 0.5 |
| Mt-2 | −2.3 ± 0.3 | −1.5 ± 0.2 |
| c-jun | −2.0 ± 0.3 | — |
| lysyl oxidase | −2.4 ± 0.4 | — |
| Hif-1α | −2.0 ± 0.2 | — |
HeLa cells were treated with 100 μM hemin (H) or 100 μM ferric ammonium citrate (FAC) for 8 hours. Total RNA was extracted and analyzed on the IronChip in comparison with an untreated control sample. The average ratios of differentially expressed genes are indicated with their standard deviations.
— indicates no significant change in mRNA levels.