Expression increase in iron-loaded and -deficient cells
| Treatment and gene name . | Increase . | H/D . |
|---|---|---|
| Iron-loaded | ||
| HO-1 | 10.3 ± 1.5 | 10.3 |
| Hsp70D | 6.4 ± 4.3 | 6.4 |
| Hsp105α | 5.4 ± 2.5 | 5.4 |
| mHsp70 | 2.0 ± 0.2 | 2.0 |
| c-myc | 2.6 ± 0.3 | 2.6 |
| L-Fer | 2.3 ± 0.2 | 2.3 |
| Gas-1 | 1.7 ± 0.2 | 1.7 |
| Gas-3 | 1.8 ± 0.2 | 1.8 |
| Iron-deficient | ||
| TfR-1 | 5.0 ± 2.2 | 0.2 |
| DMT-1 | 2.0 ± 0.4 | 0.5 |
| c-jun | 2.7 ± 0.4 | 0.4 |
| Mt-2 | 2.6 ± 0.6 | 0.4 |
| lysyl oxidase | 2.4 ± 0.4 | 0.4 |
| Hif-1α | 1.5 ± 0.2 | 0.7 |
| Treatment and gene name . | Increase . | H/D . |
|---|---|---|
| Iron-loaded | ||
| HO-1 | 10.3 ± 1.5 | 10.3 |
| Hsp70D | 6.4 ± 4.3 | 6.4 |
| Hsp105α | 5.4 ± 2.5 | 5.4 |
| mHsp70 | 2.0 ± 0.2 | 2.0 |
| c-myc | 2.6 ± 0.3 | 2.6 |
| L-Fer | 2.3 ± 0.2 | 2.3 |
| Gas-1 | 1.7 ± 0.2 | 1.7 |
| Gas-3 | 1.8 ± 0.2 | 1.8 |
| Iron-deficient | ||
| TfR-1 | 5.0 ± 2.2 | 0.2 |
| DMT-1 | 2.0 ± 0.4 | 0.5 |
| c-jun | 2.7 ± 0.4 | 0.4 |
| Mt-2 | 2.6 ± 0.6 | 0.4 |
| lysyl oxidase | 2.4 ± 0.4 | 0.4 |
| Hif-1α | 1.5 ± 0.2 | 0.7 |
The average ratios of differentially expressed genes in hemin (H)– and desferrioxamine (D)–treated cells (H/D) are indicated. The standard deviations are shown.