Anti-KLH Ab levels (μg/mL) in IUT, TBI and control mice
| Mouse group4-150 . | IgM . | IgG1 . | IgG2b . |
|---|---|---|---|
| C57Bl/6 control | 34 ± 35 | 427 ± 333 | 32 ± 50 |
| BALB/c control | 65 ± 34 | 933 ± 266 | 93 ± 115 |
| Congenic IUT | 13 ± 8 | 539 ± 478 | 7 ± 10 |
| Allo NTCD IUT | 25 ± 21 | 39 ± 77 | 2 ± 3 |
| Allo TCD IUT | 25 ± 21 | 26 ± 33 | 21 ± 31 |
| Allo TBI | 42 ± 38 | 208 ± 110 | 96 ± 82 |
| Mouse group4-150 . | IgM . | IgG1 . | IgG2b . |
|---|---|---|---|
| C57Bl/6 control | 34 ± 35 | 427 ± 333 | 32 ± 50 |
| BALB/c control | 65 ± 34 | 933 ± 266 | 93 ± 115 |
| Congenic IUT | 13 ± 8 | 539 ± 478 | 7 ± 10 |
| Allo NTCD IUT | 25 ± 21 | 39 ± 77 | 2 ± 3 |
| Allo TCD IUT | 25 ± 21 | 26 ± 33 | 21 ± 31 |
| Allo TBI | 42 ± 38 | 208 ± 110 | 96 ± 82 |
Mice were immunized with KLH in CFA at day 0 and with KLH in IFA at day 14. Sera were obtained 7 days after the second immunization and anti-KLH Ab levels were determined by sandwich ELISA. Values are mean ± SD. IUT mice were immunized starting at 12 weeks of age. TBI mice were challenged starting at 12 weeks after transplantation.
n values for each group range from 13 to 16.