Comparison of demographic and clinical characteristics of 252 patients who achieved remission and were evaluated for occult leukemia by flow cytometry
| . | Flow+ N = 41 . | Flow− N = 211 . | P . | ||
|---|---|---|---|---|---|
| . | n . | % . | n . | % . | |
| Age, in years | .765 | ||||
| 0-2 | 9 | 22 | 44 | 21 | |
| 2-10 | 12 | 29 | 65 | 31 | |
| 10-21 | 20 | 49 | 102 | 48 | |
| Sex | .719 | ||||
| Male | 24 | 59 | 114 | 54 | |
| Female | 17 | 41 | 97 | 46 | |
| Race | .328 | ||||
| White | 26 | 65 | 148 | 70 | .490 |
| Black | 7 | 18 | 15 | 7 | .060 |
| Hispanic | 4 | 10 | 28 | 13 | .796 |
| Asian | 1 | 3 | 6 | 3 | > .99 |
| Other | 2 | 5 | 13 | 6 | > .99 |
| WBC count, median | 15.45 | 18.75 | .839 | ||
| Hemoglobin level, median | 7.5 | 8.2 | .504 | ||
| Platelet count, median | 60.0 | 46.5 | .249 | ||
| FAB | .082 | ||||
| M0 | 2 | 5 | 5 | 2 | .309 |
| M1 | 10 | 25 | 31 | 15 | .159 |
| M2 | 5 | 13 | 69 | 33 | .370 |
| M4 | 11 | 28 | 49 | 23 | .549 |
| M5 | 5 | 13 | 32 | 15 | .810 |
| M6 | 2 | 5 | 3 | 1 | .181 |
| M7 | 2 | 5 | 13 | 6 | > .99 |
| MDS (NOS) | 0 | 0 | 1 | 0 | > .99 |
| RAEB | 0 | 0 | 2 | 1 | > .99 |
| RAEB-T | 2 | 5 | 6 | 3 | .617 |
| Other | 1 | 3 | 0 | 0 | .159 |
| Splenomegaly | 12 | 29 | 63 | 30 | .940 |
| Hepatomegaly | 12 | 29 | 62 | 29 | .988 |
| Cytogenetics* | .066 | ||||
| Normal | 9 | 38 | 24 | 19 | .057 |
| t(15;17) | 1 | 4 | 0 | 0 | .158 |
| t(8; 21) | 1 | 4 | 33 | 26 | .017 |
| Abnormal 16 | 2 | 8 | 16 | 13 | .740 |
| Abnormal 11 | 5 | 21 | 32 | 25 | .799 |
| t(6;9) | 1 | 4 | 2 | 2 | .405 |
| −7/7q- | 0 | 0 | 2 | 2 | > .99 |
| +8 | 2 | 8 | 5 | 4 | .305 |
| +21 | 0 | 0 | 1 | 1 | > .99 |
| Pseudodiploid | 3 | 13 | 8 | 6 | .381 |
| Hyperdiploid | 0 | 0 | 5 | 4 | > .99 |
| . | Flow+ N = 41 . | Flow− N = 211 . | P . | ||
|---|---|---|---|---|---|
| . | n . | % . | n . | % . | |
| Age, in years | .765 | ||||
| 0-2 | 9 | 22 | 44 | 21 | |
| 2-10 | 12 | 29 | 65 | 31 | |
| 10-21 | 20 | 49 | 102 | 48 | |
| Sex | .719 | ||||
| Male | 24 | 59 | 114 | 54 | |
| Female | 17 | 41 | 97 | 46 | |
| Race | .328 | ||||
| White | 26 | 65 | 148 | 70 | .490 |
| Black | 7 | 18 | 15 | 7 | .060 |
| Hispanic | 4 | 10 | 28 | 13 | .796 |
| Asian | 1 | 3 | 6 | 3 | > .99 |
| Other | 2 | 5 | 13 | 6 | > .99 |
| WBC count, median | 15.45 | 18.75 | .839 | ||
| Hemoglobin level, median | 7.5 | 8.2 | .504 | ||
| Platelet count, median | 60.0 | 46.5 | .249 | ||
| FAB | .082 | ||||
| M0 | 2 | 5 | 5 | 2 | .309 |
| M1 | 10 | 25 | 31 | 15 | .159 |
| M2 | 5 | 13 | 69 | 33 | .370 |
| M4 | 11 | 28 | 49 | 23 | .549 |
| M5 | 5 | 13 | 32 | 15 | .810 |
| M6 | 2 | 5 | 3 | 1 | .181 |
| M7 | 2 | 5 | 13 | 6 | > .99 |
| MDS (NOS) | 0 | 0 | 1 | 0 | > .99 |
| RAEB | 0 | 0 | 2 | 1 | > .99 |
| RAEB-T | 2 | 5 | 6 | 3 | .617 |
| Other | 1 | 3 | 0 | 0 | .159 |
| Splenomegaly | 12 | 29 | 63 | 30 | .940 |
| Hepatomegaly | 12 | 29 | 62 | 29 | .988 |
| Cytogenetics* | .066 | ||||
| Normal | 9 | 38 | 24 | 19 | .057 |
| t(15;17) | 1 | 4 | 0 | 0 | .158 |
| t(8; 21) | 1 | 4 | 33 | 26 | .017 |
| Abnormal 16 | 2 | 8 | 16 | 13 | .740 |
| Abnormal 11 | 5 | 21 | 32 | 25 | .799 |
| t(6;9) | 1 | 4 | 2 | 2 | .405 |
| −7/7q- | 0 | 0 | 2 | 2 | > .99 |
| +8 | 2 | 8 | 5 | 4 | .305 |
| +21 | 0 | 0 | 1 | 1 | > .99 |
| Pseudodiploid | 3 | 13 | 8 | 6 | .381 |
| Hyperdiploid | 0 | 0 | 5 | 4 | > .99 |
RAEB indicates refractory anemia with excess blasts; RAEB-T, refractory anemia with excess blasts in transformation.
For cytogenetics: N = 24 for Flow+; N = 128 for Flow−.