Flow cytometry analysis of platelets from mice expressing an IL-4Rα/GP Ibα fusion in a model of murine Bernard-Soulier syndrome
. | No. of animals tested . | Anti–IL-4R fluorescence/geometric mean (SD) . | Forward scatter/geometric mean (SD) . | Platelet count, × 109/L (SD) . |
---|---|---|---|---|
WT | 14 | 2.42 (0.19) | 17.44 (2.10) | 1373 (278) |
GP Ibα−/− | 56 | 2.64 (0.20) | 61.84 (9.52) | 382 (92) |
Tg33 (GP Ibα−/−) | 46 | 68.10 (11.17) | 30.52 (4.84) | 905 (178) |
Tg51 (GP Ibα−/−) | 11 | 109.78 (10.77) | 38.73 (5.39) | 885 (222) |
. | No. of animals tested . | Anti–IL-4R fluorescence/geometric mean (SD) . | Forward scatter/geometric mean (SD) . | Platelet count, × 109/L (SD) . |
---|---|---|---|---|
WT | 14 | 2.42 (0.19) | 17.44 (2.10) | 1373 (278) |
GP Ibα−/− | 56 | 2.64 (0.20) | 61.84 (9.52) | 382 (92) |
Tg33 (GP Ibα−/−) | 46 | 68.10 (11.17) | 30.52 (4.84) | 905 (178) |
Tg51 (GP Ibα−/−) | 11 | 109.78 (10.77) | 38.73 (5.39) | 885 (222) |