Table 1.

Flow cytometry analysis of platelets from mice expressing an IL-4Rα/GP Ibα fusion in a model of murine Bernard-Soulier syndrome

No. of animals testedAnti–IL-4R fluorescence/geometric mean (SD)Forward scatter/geometric mean (SD)Platelet count, × 109/L (SD)
WT 14 2.42  (0.19) 17.44  (2.10) 1373  (278)  
GP Ibα−/− 56 2.64  (0.20) 61.84  (9.52) 382  (92)  
Tg33 (GP Ibα−/−46 68.10  (11.17) 30.52  (4.84) 905  (178)  
Tg51 (GP Ibα−/−11 109.78  (10.77) 38.73  (5.39) 885  (222) 
No. of animals testedAnti–IL-4R fluorescence/geometric mean (SD)Forward scatter/geometric mean (SD)Platelet count, × 109/L (SD)
WT 14 2.42  (0.19) 17.44  (2.10) 1373  (278)  
GP Ibα−/− 56 2.64  (0.20) 61.84  (9.52) 382  (92)  
Tg33 (GP Ibα−/−46 68.10  (11.17) 30.52  (4.84) 905  (178)  
Tg51 (GP Ibα−/−11 109.78  (10.77) 38.73  (5.39) 885  (222) 
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