Demographics, disease history, and characteristics of patients at baseline
| Characteristics . | ALL, n = 48 . | LyBC, n = 8 . |
|---|---|---|
| Age, y | ||
| Median (range) | 50 (22-78) | 60 (49-68) |
| Sex, no. (%) | ||
| Male | 24 (50) | 4 (50) |
| Female | 24 (50) | 4 (50) |
| ECOG score, no. (%) | ||
| Grade 0-1 | 26 (54) | 5 (62) |
| Grade 2 | 19 (40) | 3 (38) |
| Grade 3 | 1 (2) | 0 |
| NA | 2 (4) | 0 |
| Prior response, no. (%) | ||
| Relapsed after first remission | 19 (40) | 3 (38) |
| Relapsed after 2 or more remissions | 12 (25) | 3 (38) |
| Refractory | 17 (35) | 2 (25) |
| Prior BMT, no. (%) | 10 (21) | 0 |
| Diagnosis to study entry, mo | ||
| Median | 8 | 5 |
| Range | 2-118 | 0-14 |
| WBC (× 109/L) | ||
| Median | 10 | 13 |
| Range | 0.2-195 | 3-106 |
| Blasts in peripheral blood, % | ||
| Median | 18 | 1 |
| Range | 0-94 | 0-84 |
| Blasts in bone marrow, % | ||
| Median | 83 | 50 |
| Range | 3-100 | 13-95 |
| Platelets (× 109/L) | ||
| Median | 32 | 108 |
| Range | 1-1715 | 9-1059 |
| Characteristics . | ALL, n = 48 . | LyBC, n = 8 . |
|---|---|---|
| Age, y | ||
| Median (range) | 50 (22-78) | 60 (49-68) |
| Sex, no. (%) | ||
| Male | 24 (50) | 4 (50) |
| Female | 24 (50) | 4 (50) |
| ECOG score, no. (%) | ||
| Grade 0-1 | 26 (54) | 5 (62) |
| Grade 2 | 19 (40) | 3 (38) |
| Grade 3 | 1 (2) | 0 |
| NA | 2 (4) | 0 |
| Prior response, no. (%) | ||
| Relapsed after first remission | 19 (40) | 3 (38) |
| Relapsed after 2 or more remissions | 12 (25) | 3 (38) |
| Refractory | 17 (35) | 2 (25) |
| Prior BMT, no. (%) | 10 (21) | 0 |
| Diagnosis to study entry, mo | ||
| Median | 8 | 5 |
| Range | 2-118 | 0-14 |
| WBC (× 109/L) | ||
| Median | 10 | 13 |
| Range | 0.2-195 | 3-106 |
| Blasts in peripheral blood, % | ||
| Median | 18 | 1 |
| Range | 0-94 | 0-84 |
| Blasts in bone marrow, % | ||
| Median | 83 | 50 |
| Range | 3-100 | 13-95 |
| Platelets (× 109/L) | ||
| Median | 32 | 108 |
| Range | 1-1715 | 9-1059 |
NA indicates not available.