Table 1.

The ratio of ΔGT- to GTGT-containing sequence in unaffected individuals and carriers of A47°CGD

Population groupMethod 1:
electropherogram
Method 2:
PCR product size*
Average
No.RatioNo.Ratio
Unaffected controls 44 2.25 ± 0.14 1.66 ± 0.12 2.16  (2:1)  
 1.02 ± 0.05 0.86 ± 0.07 0.96  (1:1)  
 0.46 ± 0.03 0.46 ± 0.02 0.46  (1:2)  
A47°CGD carriers 5.97 ± 0.64 3.69 ± 0.23 4.83  (5:1) 
 2.27 ± 0.01 — nd 2.27  (2:1) 
Population groupMethod 1:
electropherogram
Method 2:
PCR product size*
Average
No.RatioNo.Ratio
Unaffected controls 44 2.25 ± 0.14 1.66 ± 0.12 2.16  (2:1)  
 1.02 ± 0.05 0.86 ± 0.07 0.96  (1:1)  
 0.46 ± 0.03 0.46 ± 0.02 0.46  (1:2)  
A47°CGD carriers 5.97 ± 0.64 3.69 ± 0.23 4.83  (5:1) 
 2.27 ± 0.01 — nd 2.27  (2:1) 

nd indicates not determined.

*

All samples included under method 2 were also analyzed using method 1.

Mean ± SD.

Average of the 2 methods with predicted ratio in parentheses.

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