Increased immunoglobulin levels in transgenic blood serum
| Immunoglobulins . | IgE (μg/mL) . | IgM (μg/mL) . | IgG1 (μg/mL) . | IgG2A (μg/mL) . |
|---|---|---|---|---|
| Nontransgenic | 0.7 | 213.0 | 164.2 | 83.0 |
| Transgenic | 49.3 | 3824.4 | 1852.6 | 47.0 |
| Fold increase (range) | 40-80× | 10-30× | 8-20× | — |
| Immunoglobulins . | IgE (μg/mL) . | IgM (μg/mL) . | IgG1 (μg/mL) . | IgG2A (μg/mL) . |
|---|---|---|---|---|
| Nontransgenic | 0.7 | 213.0 | 164.2 | 83.0 |
| Transgenic | 49.3 | 3824.4 | 1852.6 | 47.0 |
| Fold increase (range) | 40-80× | 10-30× | 8-20× | — |
Nontransgenic and transgenic sera were measured by ELISA for the indicated immunoglobulins. Values are reported as the mean for NTg, n = 4 animals and Tg, n = 5 animals.