Table 3. Increased cytokine and... | American Society of Hematology

Table 3.

Increased cytokine and immunoglobulin levels in transgenic blood serum

Cytokines (pg/mL)	IL-2	IL-4	IL-5	G-CSF	Eotaxin	IFN-γ
Nontransgenic	ND	ND	ND	87.5	226.2	3.32
Transgenic	65.26^3-151	346.63^3-151	97.62^3-150	328.0^3-151	721.2	2264.9
Fold increase (range)	20-150×	180-500×	60-80×	2-8×	2-5×	12-2500×

Cytokines (pg/mL)	IL-2	IL-4	IL-5	G-CSF	Eotaxin	IFN-γ
Nontransgenic	ND	ND	ND	87.5	226.2	3.32
Transgenic	65.26^3-151	346.63^3-151	97.62^3-150	328.0^3-151	721.2	2264.9
Fold increase (range)	20-150×	180-500×	60-80×	2-8×	2-5×	12-2500×

Nontransgenic and transgenic sera were measured by ELISA for the indicated cytokines and immunoglobulins. Values are reported as the mean for NTg, n = 5 animals and Tg, n = 4 animals, unless otherwise indicated for cytokines.

ND indicates not detectable.

F3-150

Tg, n = 7.

F3-151

Tg, n = 3.

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