Table 1.

Spleen weights and peripheral blood leukocyte counts in IL-17E transgenic mice*

Spleen wt.
(% body weight, g)
Total WBC (103cells/μL)Neutrophils (103 cells/μL)Eosinophils (103 cells/μL)Lymphocytes (103cells/μL)Lg unstained (103 cells/μL)
Transgenics 1.08 ± 0.27 11.93 ± 4.47 2.29 ± 0.67 1.99 ± 0.38 6.76 ± 2.32 1.41 ± 1.11 
Nontransgenics 0.37 ± 0.33 3.09 ± 0.79 0.92 ± 0.53 0.03 ± 0.01 1.99 ± 0.38 0.10 ± 0.05 
P .0007 .003 .032 .017 .0025 .031 
Spleen wt.
(% body weight, g)
Total WBC (103cells/μL)Neutrophils (103 cells/μL)Eosinophils (103 cells/μL)Lymphocytes (103cells/μL)Lg unstained (103 cells/μL)
Transgenics 1.08 ± 0.27 11.93 ± 4.47 2.29 ± 0.67 1.99 ± 0.38 6.76 ± 2.32 1.41 ± 1.11 
Nontransgenics 0.37 ± 0.33 3.09 ± 0.79 0.92 ± 0.53 0.03 ± 0.01 1.99 ± 0.38 0.10 ± 0.05 
P .0007 .003 .032 .017 .0025 .031 
*

Values for IL-17E founders (n = 4, for each set of nontransgenic and transgenic mice).

Transgenic spleens, n = 5.

Large unstained cells, possibly large granular lymphocytes.

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