Table 3. Outcomes of 13 women with 22... | American Society of Hematology

Table 3.

Outcomes of 13 women with 22 pregnancies following recovery from TTP

Woman	Pregnancy	Pregnancy outcome	Child outcome
1	1	Normal	Normal
1	2	Normal	Normal
2	3	13 wk fetal loss	NA
2	4	12 wk fetal loss	NA
3	5	Normal	Normal
3	6	Normal	Normal
4	7	Severe preeclampsia	Normal
4	8	Severe preeclampsia	Normal
5	9	Normal	Normal
5	10	Normal	Normal
6	11	Preeclampsia	Normal
6	12	Preeclampsia, TTP relapse 29 d postpartum	Normal
7	13	Severe preeclampsia, TTP relapse 9 d postpartum	Normal
8	14	20 wk fetal loss	NA
	15	Normal	Normal
	16	Normal	Normal
9	17	Normal	Normal
10	18	SLE flare	Normal
11	19	Normal	Normal
11	20	Normal	Normal
12	21	Fetal growth retardation, delivery at 26 wk	Died, sepsis
13	22	Preeclampsia	Normal

Woman	Pregnancy	Pregnancy outcome	Child outcome
1	1	Normal	Normal
1	2	Normal	Normal
2	3	13 wk fetal loss	NA
2	4	12 wk fetal loss	NA
3	5	Normal	Normal
3	6	Normal	Normal
4	7	Severe preeclampsia	Normal
4	8	Severe preeclampsia	Normal
5	9	Normal	Normal
5	10	Normal	Normal
6	11	Preeclampsia	Normal
6	12	Preeclampsia, TTP relapse 29 d postpartum	Normal
7	13	Severe preeclampsia, TTP relapse 9 d postpartum	Normal
8	14	20 wk fetal loss	NA
	15	Normal	Normal
	16	Normal	Normal
9	17	Normal	Normal
10	18	SLE flare	Normal
11	19	Normal	Normal
11	20	Normal	Normal
12	21	Fetal growth retardation, delivery at 26 wk	Died, sepsis
13	22	Preeclampsia	Normal

Sixteen pregnancies in women 1 through 10 were previously reported.²⁷ Women 5 and 8 have had an additional normal pregnancy since this previous publication. No women received prophylactic treatments for TTP (eg, rituximab) preceding or during their pregnancies. Women 1, 3, 9, and 13 each had 1 previous pregnancy that was associated with their initial episode of TTP, occurring at 7 weeks’ gestation, the day of delivery, postpartum day 9 and postpartum day 45. Only woman 9 has had relapse episodes of TTP following these pregnancies; she had 2 relapses (not associated with a pregnancy) 25 and 35 months following her normal pregnancy. Woman 12 is currently pregnant, due in September 2018.

NA, child outcome when fetal loss occurred before the gestational age of viability.

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