Depression screening was performed by the Beck Depression Index-II (BDI-II) in 52 patients following their recovery from TTP from 2004 to 2014. Individual patients were tested 1 to 6 times. Levels of depression were assigned according to BDI-II criteria. The results are reported as severe (on ≥1 screening test), moderate (on ≥1 screening test but never severe), mild (on ≥1 screening test but never moderate or severe), and minimal/none (on all screening tests). Patients with severe depression have also been evaluated by a psychiatric interview to confirm the diagnosis of major depressive disorder.¹⁷ 

Cognitive testing was performed with the Repeatable Battery for Assessment of Neuropsychological Status (RBANS) in 36 patients following their recovery from TTP (2014). Five individual domains were assessed: immediate memory, delayed memory, attention, language, and visuospatial ability. Levels of cognitive ability were assigned according to normal population values adjusted for age.¹⁷