Prognostic factors for FFS (Cox univariate analysis)
| Variable . | RL . | RR . | CI 95% . | P . |
|---|---|---|---|---|
| Age | ≤ 65 | 1.36 | 0.55 -3.34 | .49 |
| Sex | Female | 0.83 | 0.32 -2.17 | .76 |
| LDH | Normal | 1.27 | 0.48 -3.32 | .61 |
| ECOG (2-3) | 0-1 | 1.84 | 0.65 -5.15 | .24 |
| Bone marrow involvement8-150 | ||||
| Liver involvement | Absent | 2.48 | 1.02 -6.03 | .043 |
| Involvement of nonhematopoietic sites | Absent | 2.21 | 0.50 -9.62 | .209 |
| Nodal involvement | Absent | 1.66 | 0.68 -4.03 | .26 |
| Response to therapy | ||||
| Noncomplete | Complete | 3.22 | 1.04 -9.98 | .032 |
| Chemotherapy | ||||
| 1 | 0 | 1.13 | 0.38 -3.37 | .82 |
| 2 | 0 | 0.54 | 0.11 -2.62 | .44 |
| 3 | 0 | 1.49 | 0.44 -5.06 | .51 |
| Mib-1 | ≤ 23 | 1.19 | 0.39 -3.59 | .75 |
| p53 | Negative | 2.43 | 0.54 -11.55 | .26 |
| del7q | Positive | 2.28 | 0.68 -7.64 | .17 |
| Variable . | RL . | RR . | CI 95% . | P . |
|---|---|---|---|---|
| Age | ≤ 65 | 1.36 | 0.55 -3.34 | .49 |
| Sex | Female | 0.83 | 0.32 -2.17 | .76 |
| LDH | Normal | 1.27 | 0.48 -3.32 | .61 |
| ECOG (2-3) | 0-1 | 1.84 | 0.65 -5.15 | .24 |
| Bone marrow involvement8-150 | ||||
| Liver involvement | Absent | 2.48 | 1.02 -6.03 | .043 |
| Involvement of nonhematopoietic sites | Absent | 2.21 | 0.50 -9.62 | .209 |
| Nodal involvement | Absent | 1.66 | 0.68 -4.03 | .26 |
| Response to therapy | ||||
| Noncomplete | Complete | 3.22 | 1.04 -9.98 | .032 |
| Chemotherapy | ||||
| 1 | 0 | 1.13 | 0.38 -3.37 | .82 |
| 2 | 0 | 0.54 | 0.11 -2.62 | .44 |
| 3 | 0 | 1.49 | 0.44 -5.06 | .51 |
| Mib-1 | ≤ 23 | 1.19 | 0.39 -3.59 | .75 |
| p53 | Negative | 2.43 | 0.54 -11.55 | .26 |
| del7q | Positive | 2.28 | 0.68 -7.64 | .17 |
For Chemotherapy, 0 indicates no chemotherapy; 1, CHOP-like; 2, clorambucil-prednisone; 3, other.
RL indicates reference level; RR, relative risk; CI, confidence interval.
Bone marrow could not be analyzed because of colinearity (see text).