Prognostic factors for OS (Cox univariate analysis)
| Variable . | RL . | RR . | CI 95% . | P . |
|---|---|---|---|---|
| Age | ≤ 65 | 3.87 | 1.27 -11.77 | .16 |
| Sex | Female | 2.08 | 0.77 -5.6 | .14 |
| LDH | Normal | 0.63 | 0.19 -2.07 | .45 |
| ECOG (2-3) | 0-1 | 4.11 | 1.46 -11.55 | .0074 |
| Bone marrow involvement | Absent | 0.95 | 0.21 -4.23 | .95 |
| Liver involvement | Absent | 4.11 | 1.46 -11.55 | .08 |
| Involvement of nonhematopoietic sites | Absent | 3.54 | 0.99 -12.7 | .05 |
| Nodal involvement | Absent | 1.84 | 0.68 -5.00 | .22 |
| Response to therapy | Complete | 9.80 | 1.25 -76.36 | .029 |
| Chemotherapy | ||||
| 1 | 0 | 1:0.83 | 0.20 -3.41 | .79 |
| 2 | 0 | 2:1.08 | 0.26 -4.43 | .90 |
| 3 | 0 | 3:2.00 | 0.55 -7.20 | .28 |
| Mib-1 | ≤ 23 | 1.02 | 0.28 -3.60 | .97 |
| p53 | Negative | 4.93 | 1.46 -16.66 | .01 |
| del7q | Positive | 1.42 | 0.35 -5.37 | .6 |
| Variable . | RL . | RR . | CI 95% . | P . |
|---|---|---|---|---|
| Age | ≤ 65 | 3.87 | 1.27 -11.77 | .16 |
| Sex | Female | 2.08 | 0.77 -5.6 | .14 |
| LDH | Normal | 0.63 | 0.19 -2.07 | .45 |
| ECOG (2-3) | 0-1 | 4.11 | 1.46 -11.55 | .0074 |
| Bone marrow involvement | Absent | 0.95 | 0.21 -4.23 | .95 |
| Liver involvement | Absent | 4.11 | 1.46 -11.55 | .08 |
| Involvement of nonhematopoietic sites | Absent | 3.54 | 0.99 -12.7 | .05 |
| Nodal involvement | Absent | 1.84 | 0.68 -5.00 | .22 |
| Response to therapy | Complete | 9.80 | 1.25 -76.36 | .029 |
| Chemotherapy | ||||
| 1 | 0 | 1:0.83 | 0.20 -3.41 | .79 |
| 2 | 0 | 2:1.08 | 0.26 -4.43 | .90 |
| 3 | 0 | 3:2.00 | 0.55 -7.20 | .28 |
| Mib-1 | ≤ 23 | 1.02 | 0.28 -3.60 | .97 |
| p53 | Negative | 4.93 | 1.46 -16.66 | .01 |
| del7q | Positive | 1.42 | 0.35 -5.37 | .6 |
For chemotherapy, 0 indicates no chemotherapy; 1, CHOP-like; 2, clorambucil-prednisone; and 3, other.
RL indicates reference level; RR, relative risk; CI, confidence interval.