HLA-DR15 and HLA-DR2 antigen frequencies in North American white MDS and AA compared with North American white control groups
| Cohort . | Group 1 (NIH): HLA-DR15 . | Group 2 (IBMTR): HLA-DR2 . | ||||
|---|---|---|---|---|---|---|
| No. . | Antigen frequency (%) . | P . | No. . | Antigen frequency (%) . | P . | |
| MDS | 72 | 26 (36) | .01 | 341 | 102 (30) | .089 |
| RA | 46 | 21 (46) | .000 48 | 84 | 30 (36) | .036 |
| RAEB | 17 | 3 (18) | .72 | 118 | 33 (28) | .53 |
| RARS | 9 | 2 (22) | .94 | 14 | 1 (7) | .11 |
| RAEB-T | — | — | — | 125 | 38 (30) | .22 |
| AA | 59 | 25 (42) | .000 8 | 364 | 119 (32) | .0059 |
| North American white | 240 | 51 (21) | — | 1145 | 290 (25) | — |
| Cohort . | Group 1 (NIH): HLA-DR15 . | Group 2 (IBMTR): HLA-DR2 . | ||||
|---|---|---|---|---|---|---|
| No. . | Antigen frequency (%) . | P . | No. . | Antigen frequency (%) . | P . | |
| MDS | 72 | 26 (36) | .01 | 341 | 102 (30) | .089 |
| RA | 46 | 21 (46) | .000 48 | 84 | 30 (36) | .036 |
| RAEB | 17 | 3 (18) | .72 | 118 | 33 (28) | .53 |
| RARS | 9 | 2 (22) | .94 | 14 | 1 (7) | .11 |
| RAEB-T | — | — | — | 125 | 38 (30) | .22 |
| AA | 59 | 25 (42) | .000 8 | 364 | 119 (32) | .0059 |
| North American white | 240 | 51 (21) | — | 1145 | 290 (25) | — |
Unclassified MDS (North American white, n = 33; DR15, n = 9) was excluded from the analysis.
No. indicates no. in cohort; P, significant differences between patient cohort and North American white control population (χ2 test).