Table 1.

Combinations of markers used for immunophenotypic characterization of MDS, with their respective cellular reactivity in BM

Cy5Cellular reactivityPECellular reactivityFITCCellular reactivity
CD45 Leucocytes —  —  
CD45  CD16 Mature granulocytes, macrophages CD14 Monocytes 
CD45  CD11c Monocytes, macrophages, granulocytes (weak) CD36 Monocytes, platelets, erythrocytes 
CD45  CD33 Myeloid progenitors/precursors, granulocytes (weak), monocytes CD15 Mature myeloid cells 
CD45  CD38 Hematopoietic stem cells, myeloid cell, monocytes, subsets of
B and/or T lymphocytes 		CD36 Monocytes, platelets, erythrocytes  
CD45  CD13 Myeloid cells CD11b Myeloid cells, monocytes 
CD45  CD56 Subset of AML 2 with t(8;21), NK, subset of T cells, plasma cells DR Hematopoietic precursors, monocytes, B cells,
subsets of activated T lymphocytes 
CD45  CD7 T-cell lineage, pluripotent hematopoietic stem cells CD2 NK and T-cell lineage, some AMLs 
CD45  CD34 Hematopoietic stem cells from both lymphoid and myeloid lineage CD71 Hematopoietic precursors, monocytes, erythrocytes  
CD45  CD19 B-cell lineage, subset of AML 2 with t(8;21) CD34 Hematopoietic precursor from both lymphoid
and myeloid lineage  
CD45  CD117 Myeloid hematopoietic precursors CD34 Hematopoietic precursor from both lymphoid
and myeloid lineage 
Cy5Cellular reactivityPECellular reactivityFITCCellular reactivity
CD45 Leucocytes —  —  
CD45  CD16 Mature granulocytes, macrophages CD14 Monocytes 
CD45  CD11c Monocytes, macrophages, granulocytes (weak) CD36 Monocytes, platelets, erythrocytes 
CD45  CD33 Myeloid progenitors/precursors, granulocytes (weak), monocytes CD15 Mature myeloid cells 
CD45  CD38 Hematopoietic stem cells, myeloid cell, monocytes, subsets of
B and/or T lymphocytes 		CD36 Monocytes, platelets, erythrocytes  
CD45  CD13 Myeloid cells CD11b Myeloid cells, monocytes 
CD45  CD56 Subset of AML 2 with t(8;21), NK, subset of T cells, plasma cells DR Hematopoietic precursors, monocytes, B cells,
subsets of activated T lymphocytes 
CD45  CD7 T-cell lineage, pluripotent hematopoietic stem cells CD2 NK and T-cell lineage, some AMLs 
CD45  CD34 Hematopoietic stem cells from both lymphoid and myeloid lineage CD71 Hematopoietic precursors, monocytes, erythrocytes  
CD45  CD19 B-cell lineage, subset of AML 2 with t(8;21) CD34 Hematopoietic precursor from both lymphoid
and myeloid lineage  
CD45  CD117 Myeloid hematopoietic precursors CD34 Hematopoietic precursor from both lymphoid
and myeloid lineage 

NK indicates natural killer.

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