Combinations of markers used for immunophenotypic characterization of MDS, with their respective cellular reactivity in BM
Cy5 . | Cellular reactivity . | PE . | Cellular reactivity . | FITC . | Cellular reactivity . |
---|---|---|---|---|---|
CD45 | Leucocytes | — | — | ||
CD45 | CD16 | Mature granulocytes, macrophages | CD14 | Monocytes | |
CD45 | CD11c | Monocytes, macrophages, granulocytes (weak) | CD36 | Monocytes, platelets, erythrocytes | |
CD45 | CD33 | Myeloid progenitors/precursors, granulocytes (weak), monocytes | CD15 | Mature myeloid cells | |
CD45 | CD38 | Hematopoietic stem cells, myeloid cell, monocytes, subsets of B and/or T lymphocytes | CD36 | Monocytes, platelets, erythrocytes | |
CD45 | CD13 | Myeloid cells | CD11b | Myeloid cells, monocytes | |
CD45 | CD56 | Subset of AML 2 with t(8;21), NK, subset of T cells, plasma cells | DR | Hematopoietic precursors, monocytes, B cells, subsets of activated T lymphocytes | |
CD45 | CD7 | T-cell lineage, pluripotent hematopoietic stem cells | CD2 | NK and T-cell lineage, some AMLs | |
CD45 | CD34 | Hematopoietic stem cells from both lymphoid and myeloid lineage | CD71 | Hematopoietic precursors, monocytes, erythrocytes | |
CD45 | CD19 | B-cell lineage, subset of AML 2 with t(8;21) | CD34 | Hematopoietic precursor from both lymphoid and myeloid lineage | |
CD45 | CD117 | Myeloid hematopoietic precursors | CD34 | Hematopoietic precursor from both lymphoid and myeloid lineage |
Cy5 . | Cellular reactivity . | PE . | Cellular reactivity . | FITC . | Cellular reactivity . |
---|---|---|---|---|---|
CD45 | Leucocytes | — | — | ||
CD45 | CD16 | Mature granulocytes, macrophages | CD14 | Monocytes | |
CD45 | CD11c | Monocytes, macrophages, granulocytes (weak) | CD36 | Monocytes, platelets, erythrocytes | |
CD45 | CD33 | Myeloid progenitors/precursors, granulocytes (weak), monocytes | CD15 | Mature myeloid cells | |
CD45 | CD38 | Hematopoietic stem cells, myeloid cell, monocytes, subsets of B and/or T lymphocytes | CD36 | Monocytes, platelets, erythrocytes | |
CD45 | CD13 | Myeloid cells | CD11b | Myeloid cells, monocytes | |
CD45 | CD56 | Subset of AML 2 with t(8;21), NK, subset of T cells, plasma cells | DR | Hematopoietic precursors, monocytes, B cells, subsets of activated T lymphocytes | |
CD45 | CD7 | T-cell lineage, pluripotent hematopoietic stem cells | CD2 | NK and T-cell lineage, some AMLs | |
CD45 | CD34 | Hematopoietic stem cells from both lymphoid and myeloid lineage | CD71 | Hematopoietic precursors, monocytes, erythrocytes | |
CD45 | CD19 | B-cell lineage, subset of AML 2 with t(8;21) | CD34 | Hematopoietic precursor from both lymphoid and myeloid lineage | |
CD45 | CD117 | Myeloid hematopoietic precursors | CD34 | Hematopoietic precursor from both lymphoid and myeloid lineage |
NK indicates natural killer.