Table 4.

Hematologic toxicity and transfusional requirement following high-dose etoposide, high-dose CTX, and autograft

ParametersHd VP16Hd-CTXMITO/L-PAM
Days with WBC < 0.5 × 109/L 3  (0-8) 5  (0-9) 8  (3-14)  
Days with platelets < 20 × 109/L 3  (0-7) 5  (0-10) 10  (5-20)  
Median no. of platelet transfusions (range) 0  (0-3) 1  (0-6) 3  (0-8)  
Median no. of RBC transfusions (range) 0  (0-4) 1  (0-9) 2  (0-8) 
ParametersHd VP16Hd-CTXMITO/L-PAM
Days with WBC < 0.5 × 109/L 3  (0-8) 5  (0-9) 8  (3-14)  
Days with platelets < 20 × 109/L 3  (0-7) 5  (0-10) 10  (5-20)  
Median no. of platelet transfusions (range) 0  (0-3) 1  (0-6) 3  (0-8)  
Median no. of RBC transfusions (range) 0  (0-4) 1  (0-9) 2  (0-8) 

Hd indicates high-dose; WBC, white blood cells; RBC, red blood cells.

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