Table 1.

WHO classification of acute myeloid leukemia

Acute myeloid leukemia with recurrent genetic abnormalities 
  Acute myeloid leukemia with t(8;21)(q22;q22), (AML1/ETO)  
  Acute myeloid leukemia with abnormal bone marrow eosinophils and inv(16)(p13q22) or t(16;16)(p13;q22), (CBFβ/MYH11)  
  Acute promyelocytic leukemia with t(15;17)(q22;q12), (PML/RARα) and variants  
  Acute myeloid leukemia with 11q23 (MLL) abnormalities  
 Acute myeloid leukemia with multilineage dysplasia  
  Following MDS or MDS/MPD  
  Without antecedent MDS or MDS/MPD, but with dysplasia in at least 50% of cells in 2 or more myeloid lineages  
 Acute myeloid leukemia and myelodysplastic syndromes, therapy related 
  Alkylating agent/radiation–related type  
  Topoisomerase II inhibitor–related type (some may be lymphoid)  
  Others  
 Acute myeloid leukemia, not otherwise categorized  
  Classify as: 
   Acute myeloid leukemia, minimally differentiated  
   Acute myeloid leukemia without maturation  
   Acute myeloid leukemia with maturation  
   Acute myelomonocytic leukemia  
   Acute monoblastic/acute monocytic leukemia  
   Acute erythroid leukemia (erythroid/myeloid and pure erythroleukemia)  
   Acute megakaryoblastic leukemia  
   Acute basophilic leukemia 
   Acute panmyelosis with myelofibrosis  
   Myeloid sarcoma 
Acute myeloid leukemia with recurrent genetic abnormalities 
  Acute myeloid leukemia with t(8;21)(q22;q22), (AML1/ETO)  
  Acute myeloid leukemia with abnormal bone marrow eosinophils and inv(16)(p13q22) or t(16;16)(p13;q22), (CBFβ/MYH11)  
  Acute promyelocytic leukemia with t(15;17)(q22;q12), (PML/RARα) and variants  
  Acute myeloid leukemia with 11q23 (MLL) abnormalities  
 Acute myeloid leukemia with multilineage dysplasia  
  Following MDS or MDS/MPD  
  Without antecedent MDS or MDS/MPD, but with dysplasia in at least 50% of cells in 2 or more myeloid lineages  
 Acute myeloid leukemia and myelodysplastic syndromes, therapy related 
  Alkylating agent/radiation–related type  
  Topoisomerase II inhibitor–related type (some may be lymphoid)  
  Others  
 Acute myeloid leukemia, not otherwise categorized  
  Classify as: 
   Acute myeloid leukemia, minimally differentiated  
   Acute myeloid leukemia without maturation  
   Acute myeloid leukemia with maturation  
   Acute myelomonocytic leukemia  
   Acute monoblastic/acute monocytic leukemia  
   Acute erythroid leukemia (erythroid/myeloid and pure erythroleukemia)  
   Acute megakaryoblastic leukemia  
   Acute basophilic leukemia 
   Acute panmyelosis with myelofibrosis  
   Myeloid sarcoma 
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