Table 2.

Relative hazard of ESLD during 16 years of follow-up of all participants with hepatitis C virus (HCV) infection in the MHCS

VariableNo. of participantsESLD cases (%)Relative hazard (95% CI)*
All HCV+ (n = 1816,
with 135 ESLD
cases) 
   
 HIV 624 10  (1.6) 1.0  (Referent) 
 HIV+ 1192 125  (10.5) 7.9  (4.2-15.2) 
 Age 0-16 y 718 29  (4.0) 1.0  (Referent)  
 Age 17-32 y 728 52  (7.1) 1.6  (1.0-2.5)  
 Age 33-86 y 370 54  (14.6) 5.0  (3.2-7.9)  
HCV+, HIV
(n = 624, with
10 ESLD cases) 
   
 Age 0-16 y 297 1  (0.3) 1.0  (Referent)  
 Age 17-32 y 194 2  (1.0) 3.5  (0.3-38.7) 
 Age 33-86 y 133 7  (5.3) 17.7  (2.2-143.6) 
HCV+, HIV+
(n = 1192, with
125 ESLD cases) 
   
 Age 0-16 y 421 28  (6.7) 1.0  (Referent)  
 Age 17-32 y 534 50  (9.4) 1.5  (0.96-2.4) 
 Age 33-86 y 237 47  (19.8) 4.6  (2.9-7.3) 
VariableNo. of participantsESLD cases (%)Relative hazard (95% CI)*
All HCV+ (n = 1816,
with 135 ESLD
cases) 
   
 HIV 624 10  (1.6) 1.0  (Referent) 
 HIV+ 1192 125  (10.5) 7.9  (4.2-15.2) 
 Age 0-16 y 718 29  (4.0) 1.0  (Referent)  
 Age 17-32 y 728 52  (7.1) 1.6  (1.0-2.5)  
 Age 33-86 y 370 54  (14.6) 5.0  (3.2-7.9)  
HCV+, HIV
(n = 624, with
10 ESLD cases) 
   
 Age 0-16 y 297 1  (0.3) 1.0  (Referent)  
 Age 17-32 y 194 2  (1.0) 3.5  (0.3-38.7) 
 Age 33-86 y 133 7  (5.3) 17.7  (2.2-143.6) 
HCV+, HIV+
(n = 1192, with
125 ESLD cases) 
   
 Age 0-16 y 421 28  (6.7) 1.0  (Referent)  
 Age 17-32 y 534 50  (9.4) 1.5  (0.96-2.4) 
 Age 33-86 y 237 47  (19.8) 4.6  (2.9-7.3) 

All of the age categories refer to age at the start of analysis (time = 0 at May 29, 1982, or birth date [age 0], if later).

*

Relative hazards for HIV and age are adjusted for each other in the “all HCV+” model. The lower 2 models (“HIV” and “HIV+”) included only the age categories.

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