Relative hazard of ESLD during 16 years of follow-up of all participants with hepatitis C virus (HCV) infection in the MHCS
Variable . | No. of participants . | ESLD cases (%) . | Relative hazard (95% CI)* . |
---|---|---|---|
All HCV+ (n = 1816, with 135 ESLD cases) | |||
HIV− | 624 | 10 (1.6) | 1.0 (Referent) |
HIV+ | 1192 | 125 (10.5) | 7.9 (4.2-15.2) |
Age 0-16 y | 718 | 29 (4.0) | 1.0 (Referent) |
Age 17-32 y | 728 | 52 (7.1) | 1.6 (1.0-2.5) |
Age 33-86 y | 370 | 54 (14.6) | 5.0 (3.2-7.9) |
HCV+, HIV− (n = 624, with 10 ESLD cases) | |||
Age 0-16 y | 297 | 1 (0.3) | 1.0 (Referent) |
Age 17-32 y | 194 | 2 (1.0) | 3.5 (0.3-38.7) |
Age 33-86 y | 133 | 7 (5.3) | 17.7 (2.2-143.6) |
HCV+, HIV+ (n = 1192, with 125 ESLD cases) | |||
Age 0-16 y | 421 | 28 (6.7) | 1.0 (Referent) |
Age 17-32 y | 534 | 50 (9.4) | 1.5 (0.96-2.4) |
Age 33-86 y | 237 | 47 (19.8) | 4.6 (2.9-7.3) |
Variable . | No. of participants . | ESLD cases (%) . | Relative hazard (95% CI)* . |
---|---|---|---|
All HCV+ (n = 1816, with 135 ESLD cases) | |||
HIV− | 624 | 10 (1.6) | 1.0 (Referent) |
HIV+ | 1192 | 125 (10.5) | 7.9 (4.2-15.2) |
Age 0-16 y | 718 | 29 (4.0) | 1.0 (Referent) |
Age 17-32 y | 728 | 52 (7.1) | 1.6 (1.0-2.5) |
Age 33-86 y | 370 | 54 (14.6) | 5.0 (3.2-7.9) |
HCV+, HIV− (n = 624, with 10 ESLD cases) | |||
Age 0-16 y | 297 | 1 (0.3) | 1.0 (Referent) |
Age 17-32 y | 194 | 2 (1.0) | 3.5 (0.3-38.7) |
Age 33-86 y | 133 | 7 (5.3) | 17.7 (2.2-143.6) |
HCV+, HIV+ (n = 1192, with 125 ESLD cases) | |||
Age 0-16 y | 421 | 28 (6.7) | 1.0 (Referent) |
Age 17-32 y | 534 | 50 (9.4) | 1.5 (0.96-2.4) |
Age 33-86 y | 237 | 47 (19.8) | 4.6 (2.9-7.3) |
All of the age categories refer to age at the start of analysis (time = 0 at May 29, 1982, or birth date [age 0], if later).
Relative hazards for HIV and age are adjusted for each other in the “all HCV+” model. The lower 2 models (“HIV−” and “HIV+”) included only the age categories.