Characteristics of patients with and without adenovirus infections
| . | Patients with adenovirus (n = 15) . | Patients without adenovirus (n = 61) . | P (odds ratio/95% CI) . |
|---|---|---|---|
| Median age (range) | 39 (18-52) | 38 (18-53) | 1.0 |
| Sex, male/female | 10/5 | 37/24 | .89 |
| Diagnosis | .9 | ||
| Acute/chronic leukemia | 6/7 | 31/14 | |
| Lymphoma/myeloma | 2/0 | 12/2 | |
| Severe aplastic anemia | 0 | 2 | |
| Donor, family/unrelated | 8/7 | 45/16 | .2 |
| Conditioning, conventional/nonmyeloablative | 5/10 | 46/15 | .004 (6.13/1.5-26) |
| T-cell depletion, yes/no | 15/0 | 47/14 | .05 (undefined) |
| CMV seropositive, yes/no | 6/9 | 35/26 | .3 |
| CMV reactivation/disease | 4/1 | 13/4 | .4 |
| GVHD | .6 | ||
| None | 10 | 38 | |
| Grades 1-2 | 3 | 18 | |
| Grades 3-4 (or extensive chronic) | 2 | 5 | |
| Neutrophils > 0.5 × 109/L, days after transplantation | 14 | 13.5 | |
| Non-CMV infection | 10 | 19 | .02 (4.4/1.1-18.4) |
| . | Patients with adenovirus (n = 15) . | Patients without adenovirus (n = 61) . | P (odds ratio/95% CI) . |
|---|---|---|---|
| Median age (range) | 39 (18-52) | 38 (18-53) | 1.0 |
| Sex, male/female | 10/5 | 37/24 | .89 |
| Diagnosis | .9 | ||
| Acute/chronic leukemia | 6/7 | 31/14 | |
| Lymphoma/myeloma | 2/0 | 12/2 | |
| Severe aplastic anemia | 0 | 2 | |
| Donor, family/unrelated | 8/7 | 45/16 | .2 |
| Conditioning, conventional/nonmyeloablative | 5/10 | 46/15 | .004 (6.13/1.5-26) |
| T-cell depletion, yes/no | 15/0 | 47/14 | .05 (undefined) |
| CMV seropositive, yes/no | 6/9 | 35/26 | .3 |
| CMV reactivation/disease | 4/1 | 13/4 | .4 |
| GVHD | .6 | ||
| None | 10 | 38 | |
| Grades 1-2 | 3 | 18 | |
| Grades 3-4 (or extensive chronic) | 2 | 5 | |
| Neutrophils > 0.5 × 109/L, days after transplantation | 14 | 13.5 | |
| Non-CMV infection | 10 | 19 | .02 (4.4/1.1-18.4) |