Table 3.

Multidrug resistance phenotype by treatment arm

HDAC/DNR, n = 40HDAC/DNR + CsA,
n = 37
No. positive/no. patientsPercentageNo. positive/no. patientsPercentage
Duplicate Ph 5/37 14 5/36 14 
Pgp* 20/36 56 22/36 61  
CsA-inhibited DiOC2 efflux† 22/36 61 21/36 58 
MRP1* 8/36 22 5/36 14 
LRP* 23/35 66 28/36 78 
HDAC/DNR, n = 40HDAC/DNR + CsA,
n = 37
No. positive/no. patientsPercentageNo. positive/no. patientsPercentage
Duplicate Ph 5/37 14 5/36 14 
Pgp* 20/36 56 22/36 61  
CsA-inhibited DiOC2 efflux† 22/36 61 21/36 58 
MRP1* 8/36 22 5/36 14 
LRP* 23/35 66 28/36 78 
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