Table 2. Analysis of the effect of the... | American Society of Hematology

Table 2.

Analysis of the effect of the Cdc25A alleles on the anemia and survival of Kit^Wv/Wv mice

Genotype	Hematocrit, %	Survival longer than 4 wk, %
W^v/W^v;Cdc25A^128His/Cdc25A^128His	38.1 ± 4.2	80
W^v/W^v;Cdc25A^128His/Cdc25A^128Gln	38.5 ± 3.0	67
W^v/W^v;Cdc25A^128Gln/Cdc25A^128Gln	30.5 ± 2.2^*	25

Genotype	Hematocrit, %	Survival longer than 4 wk, %
W^v/W^v;Cdc25A^128His/Cdc25A^128His	38.1 ± 4.2	80
W^v/W^v;Cdc25A^128His/Cdc25A^128Gln	38.5 ± 3.0	67
W^v/W^v;Cdc25A^128Gln/Cdc25A^128Gln	30.5 ± 2.2^*	25

P < .01.

W^v/W^v;Cdc25A^128His/Cdc25A^128His,W^v/W^v;Cdc25A^128His/Cdc25A^128Gln, andW^v/W^v;Cdc25A^128Gln/Cdc25A^128Glnmice were generated as described. Hematocrit levels were measured at 3 weeks of age. The Cdc25A^128Gln allele had no effect on the mild anemia of Kit^Wvheterozygotes.

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