Table 3. Correlation of BCL-2 expression... | American Society of Hematology

Table 3.

Correlation of BCL-2 expression in HRS cells with clinical and laboratory findings

Parameter	All patients	BCL-2⁺		P^3-150
Parameter	All patients	No.	%	P^3-150
Age, y
45 or older	143	72	50	.003
Younger than 45	564	323	64
Sex
Male	383	217	57	.005
Female	324	217	67
Stage
I	94	50	53	.008
II	358	238	66
III	142	74	52
IV	113	72	64
B symptoms
Present	258	173	68	.02
Absent	449	261	58
Serum albumin level
Low^3-151	96	64	67	.3
Normal	552	336	61
Anemia
Present	313	198	63	.4
Absent	389	232	60
Leukocytosis^3-152
Present	67	48	72	.09
Absent	635	383	60
Lymphocytopenia^3-152
Present	63	40	63	.7
Absent	574	347	60
Serum β₂-microglobulin level
High^3-151	161	92	57	.3
Normal	273	172	63
Serum LDH level
High^3-151	213	139	65	.17
Normal	414	246	59
Bone marrow involvement
Present	55	29	53	.2
Absent	652	405	62
Mediastinal mass ratio
At least 0.45	77	52	68	.2
Lower than 0.45	425	254	60
Inguinal or iliac nodes
Involved	131	79	60	.8
Uninvolved	574	354	62

Parameter	All patients	BCL-2⁺		P^3-150
Parameter	All patients	No.	%	P^3-150
Age, y
45 or older	143	72	50	.003
Younger than 45	564	323	64
Sex
Male	383	217	57	.005
Female	324	217	67
Stage
I	94	50	53	.008
II	358	238	66
III	142	74	52
IV	113	72	64
B symptoms
Present	258	173	68	.02
Absent	449	261	58
Serum albumin level
Low^3-151	96	64	67	.3
Normal	552	336	61
Anemia
Present	313	198	63	.4
Absent	389	232	60
Leukocytosis^3-152
Present	67	48	72	.09
Absent	635	383	60
Lymphocytopenia^3-152
Present	63	40	63	.7
Absent	574	347	60
Serum β₂-microglobulin level
High^3-151	161	92	57	.3
Normal	273	172	63
Serum LDH level
High^3-151	213	139	65	.17
Normal	414	246	59
Bone marrow involvement
Present	55	29	53	.2
Absent	652	405	62
Mediastinal mass ratio
At least 0.45	77	52	68	.2
Lower than 0.45	425	254	60
Inguinal or iliac nodes
Involved	131	79	60	.8
Uninvolved	574	354	62

F3-150

All P values were calculated with the Fisher exact test, except for the P between BCL-2 expression and stage I versus II versus III versus IV, which was calculated with the χ² test.

F3-151

As defined in “Patients and methods.”

F3-152

As defined by in IPS.5

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