Table 2.

Hazard ratios of recurrent thromboembolism and major bleeding in the 181 patients with malignancy as compared to the 661 cancer-free patients according to the site of malignancy

Site of cancerNo. (%)Follow-up, patient-yRecurrent VTE
hazard ratio (95% CI)
Bleeding
hazard ratio (95%CI)
Genitourinary* 47 (26.0) 26.4 3.7 (1.7-8.0) 4.5 (2.1-9.9) 
Gastrointestinal 37 (20.4) 18.4 5.1 (2.3-11.3) 1.3 (0.3-5.6) 
Breast 27 (15.0) 18.5 0.7 (0.1-4.9) 2.3 (0.7-7.9) 
Myelolymphoproliferative 24 (13.3) 18.9 2.3 (0.7-7.5) 1.6 (0.4-6.9) 
Lung 24 (13.3) 14.9 6.9 (3.0-15.9) 0.9 (0.1-7.2) 
Brain 14 (7.7) 6.2 3.7 (0.8-14.1) 0.0 
Other2-153 8 (4.4) 5.0 2.3 (0.3-16.7) 0.0 
Site of cancerNo. (%)Follow-up, patient-yRecurrent VTE
hazard ratio (95% CI)
Bleeding
hazard ratio (95%CI)
Genitourinary* 47 (26.0) 26.4 3.7 (1.7-8.0) 4.5 (2.1-9.9) 
Gastrointestinal 37 (20.4) 18.4 5.1 (2.3-11.3) 1.3 (0.3-5.6) 
Breast 27 (15.0) 18.5 0.7 (0.1-4.9) 2.3 (0.7-7.9) 
Myelolymphoproliferative 24 (13.3) 18.9 2.3 (0.7-7.5) 1.6 (0.4-6.9) 
Lung 24 (13.3) 14.9 6.9 (3.0-15.9) 0.9 (0.1-7.2) 
Brain 14 (7.7) 6.2 3.7 (0.8-14.1) 0.0 
Other2-153 8 (4.4) 5.0 2.3 (0.3-16.7) 0.0 
*

Uterus (13 patients [numbers in parentheses are numbers of patients]), kidney (9), ovary or testicle (8), bladder (9), prostate (8).

Colorectal (19), stomach or esophagus (7), pancreas (7), liver or gallbladder (4).

Chronic leukemia (11), lymphoma (8), myeloma (5).

F2-153

Melanoma (2), muscle sarcoma (2), rhinopharyngeal (1), laryngeal (1), vulvar (1), adrenal gland (1).

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