Table 1.

Hematologic parameters of wild-type, Vav1−/−, Vav2−/−, and Vav1−/− Vav2−/−mice

ParameterValue (± SD)* for genotype
Wild typeVav1−/−Vav2−/−Vav1−/−Vav2−/−P compared
with wild type
Leukocytes, 103/mL 2.82 ± 0.36 4.39 ± 1.38 6.39 ± 1.411-160 2.79 ± 1.40 NS < .0011-160 
Erythrocytes, 106/mL 9.38 ± 0.67 8.52 ± 0.23 8.85 ± 0.47 9.18 ± 0.84 NS 
Hemoglobin, g/dL 12.9 ± 0.6 12.7 ± 0.5 13.6 ± 0.9 13.7 ± 0.9 NS 
Packed cell volume, % 41 ± 1.3 38.4 ± 1.6 43.6 ± 3.1 42.4 ± 2.7 NS 
Platelets, 109/mL 653 ± 102 679 ± 80 686 ± 99 644 ± 78 NS 
ParameterValue (± SD)* for genotype
Wild typeVav1−/−Vav2−/−Vav1−/−Vav2−/−P compared
with wild type
Leukocytes, 103/mL 2.82 ± 0.36 4.39 ± 1.38 6.39 ± 1.411-160 2.79 ± 1.40 NS < .0011-160 
Erythrocytes, 106/mL 9.38 ± 0.67 8.52 ± 0.23 8.85 ± 0.47 9.18 ± 0.84 NS 
Hemoglobin, g/dL 12.9 ± 0.6 12.7 ± 0.5 13.6 ± 0.9 13.7 ± 0.9 NS 
Packed cell volume, % 41 ± 1.3 38.4 ± 1.6 43.6 ± 3.1 42.4 ± 2.7 NS 
Platelets, 109/mL 653 ± 102 679 ± 80 686 ± 99 644 ± 78 NS 

Samples of whole blood (20 μL) were analyzed using an ABX Micros 60 (ABX Diagnostics, Montpelier, France).

NS indicates not significant.

*

Data is presented as mean ± standard deviation (SD) from n = 5 mice.

F1-160

indicates Vav2−/−.

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