Cyclosporine and methotrexate levels
| Time after transplantation . | IL-1Ra . | Placebo . | P . |
|---|---|---|---|
| Cyclosporine trough (mean ± SD μg/L) | |||
| Week 1 | 225 ± 78 (n = 90) | 235 ± 81 (n = 89) | .37 |
| Week 2 | 273 ± 82 (n = 90) | 268 ± 87 (n = 89) | .66 |
| Week 3 | 259 ± 74 (n = 91) | 283 ± 94 (n = 86) | .07 |
| Week 4 | 258 ± 90 (n = 85) | 265 ± 101 (n = 86) | .64 |
| Week 5 | 256 ± 96 (n = 82) | 270 ± 129 (n = 79) | .44 |
| Prescribed dose administered, % | |||
| Day 1 | 99 | 99 | .17 |
| Day 3 | 100 | 98 | .17 |
| Day 6 | 99 | 98 | .40 |
| Day 11 | 86 | 77 | .09 |
| Time after transplantation . | IL-1Ra . | Placebo . | P . |
|---|---|---|---|
| Cyclosporine trough (mean ± SD μg/L) | |||
| Week 1 | 225 ± 78 (n = 90) | 235 ± 81 (n = 89) | .37 |
| Week 2 | 273 ± 82 (n = 90) | 268 ± 87 (n = 89) | .66 |
| Week 3 | 259 ± 74 (n = 91) | 283 ± 94 (n = 86) | .07 |
| Week 4 | 258 ± 90 (n = 85) | 265 ± 101 (n = 86) | .64 |
| Week 5 | 256 ± 96 (n = 82) | 270 ± 129 (n = 79) | .44 |
| Prescribed dose administered, % | |||
| Day 1 | 99 | 99 | .17 |
| Day 3 | 100 | 98 | .17 |
| Day 6 | 99 | 98 | .40 |
| Day 11 | 86 | 77 | .09 |