Table 2.
Treatment parameters and hematological effects of hydroxyurea therapy for very young children with SCA
In both the HUSOFT and BABY HUG trial, the hydroxyurea dose was 20 mg/kg/d for the main study, but patients were allowed to escalate to the MTD in the extension and follow-up studies. Mean values are reported. NA indicates not available. BABY HUG, Infant Hydroxyurea Group.