Table 2. Drugs most frequently reported... | American Society of Hematology

Table 2.

Drugs most frequently reported to cause IDIN

Huber et al⁷	Medrano-Casique et al⁵	Andrés et al⁹	Curtis*
Carbamazepine†	Benzylpenicillin†	Amoxicillin†	Cefipime
Clozapine†	Cefipime†	Carbimazole†	Ceftriaxone‡
Metamizole (dipyrone)†	Linezolid	Clozapine†	Ciprofloxacin‡
Sulfasalazine†	Meropenem†	Cotrimoxazole†	Clindamycin
Thiamazole†	Metronidazole	Cefotaxime	Ibuprofen
	Piperacillin-tazobactam†	Noramidopyrine	Levetiracetam
	Teicoplanin	Piperacillin-tazobactam	Piperacillin-tazobactam‡
	Tobramycin	Salazopyrine	Quetiapine
	Torsemide	Ticlopidine†	Sulfamethoxazole/trimethoprim‡
	Vancomycin†	Valganciclovir	Tacrolimus
			Vancomycin‡
			Venlafaxine

Huber et al⁷	Medrano-Casique et al⁵	Andrés et al⁹	Curtis*
Carbamazepine†	Benzylpenicillin†	Amoxicillin†	Cefipime
Clozapine†	Cefipime†	Carbimazole†	Ceftriaxone‡
Metamizole (dipyrone)†	Linezolid	Clozapine†	Ciprofloxacin‡
Sulfasalazine†	Meropenem†	Cotrimoxazole†	Clindamycin
Thiamazole†	Metronidazole	Cefotaxime	Ibuprofen
	Piperacillin-tazobactam†	Noramidopyrine	Levetiracetam
	Teicoplanin	Piperacillin-tazobactam	Piperacillin-tazobactam‡
	Tobramycin	Salazopyrine	Quetiapine
	Torsemide	Ticlopidine†	Sulfamethoxazole/trimethoprim‡
	Vancomycin†	Valganciclovir	Tacrolimus
			Vancomycin‡
			Venlafaxine

Drugs for which sera received during the period 2012 to 2016 from patients with suspicion of drug-induced immune neutropenia were tested for drug-dependent antibodies in a flow cytometry assay by Platelet & Neutrophil Immunology Lab, BloodCenter of Wisconsin, Milwaukee, WI. No drug-dependent antibodies involving these drugs were detected in any of the patients' sera.

†

Five most frequently associated drugs.

‡

Five most suspected drugs.

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