Table 5.

Alternative strategies for ICT when MRI technology is not available in NTDT

Serum ferritinStrategy
SF ≤300 ng/mL None 
SF 300-800 ng/mL None, or use other measures indicative of iron overload state, or try to obtain MRI 
SF >800 ng/mL Initiate ICT with DFX 
Serum ferritinStrategy
SF ≤300 ng/mL None 
SF 300-800 ng/mL None, or use other measures indicative of iron overload state, or try to obtain MRI 
SF >800 ng/mL Initiate ICT with DFX 

DFX, deferasirox; ICT, iron chelation therapy; SF, serum ferritin.

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