FLIPI and FLIPI-2
| Risk group . | No. of risk factors . | Outcome, % . | |
|---|---|---|---|
| 5-y OS . | 10-y OS . | ||
| FLIPI | |||
| Low | 0-1 | 91 | 71 |
| Intermediate | 2 | 78 | 51 |
| High | 3-5 | 53 | 36 |
| 3-y PFS | 5-y PFS | ||
| FLIPI-2 | |||
| Low | 0 | 91 | 80 |
| Intermediate | 1-2 | 69 | 51 |
| High | 3-5 | 51 | 19 |
| Risk group . | No. of risk factors . | Outcome, % . | |
|---|---|---|---|
| 5-y OS . | 10-y OS . | ||
| FLIPI | |||
| Low | 0-1 | 91 | 71 |
| Intermediate | 2 | 78 | 51 |
| High | 3-5 | 53 | 36 |
| 3-y PFS | 5-y PFS | ||
| FLIPI-2 | |||
| Low | 0 | 91 | 80 |
| Intermediate | 1-2 | 69 | 51 |
| High | 3-5 | 51 | 19 |
Risk factors for FLIPI are age >60 y, stage III/IV, hemoglobin <12 g/dL, LDH elevated, and >4 nodal sites; risk factors for FLIPI-2 are age >60 y, B2M elevated, hemoglobin <12 g/dL, bone marrow involvement, and lymph node diameter > 6 cm. OS, overall survival; PFS, progression-free survival.